Structure of PDB 2w95 Chain C Binding Site BS01

Receptor Information
>2w95 Chain C (length=253) Species: 366501 (Dictyostelium discoideum AX2) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MSTQGLVQLLANAQCHLRTSTNYNGVHTQFNSALNYKNNGTNTIDGSEAW
CSSIVDTNQYIVAGCEVPRTFMCVALQGRGDADQWVTSYKIRYSLDNVSW
FEYRNGAAVTGVTDRNTVVNHFFDTPIRARSIAIHPLTWNGHISLRCEFY
TQPVQSSVTQVGADIYTGDNCALNTGSGKREVVVPVKFQFEFATLPKVAL
NFDQIDCTDATNQTRIGVQPRNITTKGFDCVFYTWNENKVYSLRADYIAT
ALE
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2w95 Chain C Residue 260 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2w95 Discoidin I from Dictyostelium Discoideum and Interactions with Oligosaccharides: Specificity, Affinity, Crystal Structures and Comparison with Discoidin II.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		D164 D203 D246
Binding residue
(residue number reindexed from 1)		D164 D203 D246
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005515 protein binding
GO:0030246 carbohydrate binding
GO:0030247 polysaccharide binding
GO:0046871 N-acetylgalactosamine binding
GO:0070492 oligosaccharide binding
GO:1990458 lipooligosaccharide binding
Biological Process
GO:0000281 mitotic cytokinesis
GO:0007010 cytoskeleton organization
GO:0007155 cell adhesion
GO:0009617 response to bacterium
GO:0010468 regulation of gene expression
GO:0019954 asexual reproduction
GO:0030865 cortical cytoskeleton organization
GO:0031589 cell-substrate adhesion
GO:0061635 regulation of protein complex stability
GO:0072697 protein localization to cell cortex
GO:0098609 cell-cell adhesion
GO:0106136 lectin-induced modified bacterial internalization
GO:1902168 response to catechin
GO:1904643 response to curcumin
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005938 cell cortex
GO:0009986 cell surface
GO:0031012 extracellular matrix
GO:0045335 phagocytic vesicle
GO:0097708 intracellular vesicle
GO:0098636 protein complex involved in cell adhesion
GO:0106139 symbiont cell surface

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2w95, PDBe:2w95, PDBj:2w95
PDBsum2w95
PubMed20580724
UniProtP02886|DIS1A_DICDI Discoidin-1 subunit A (Gene Name=dscA-1)

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