Structure of PDB 2vpl Chain C Binding Site BS01
Receptor Information
>2vpl Chain C (length=137) Species:
274
(Thermus thermophilus) [
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PKHGKRYRALLEKVDPNKIYTIDEAAHLVKELATAKFDETVEVHAKLGID
PRRSDQNVRGTVSLPHGGRIEFRNDKTGAIHAPVGKASFPPEKLADNIRA
FIRALEAHKPEGAKGTFLRSVYVTTTMGPSVRINPHS
Ligand information
>2vpl Chain D (length=46) [
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ggagugaaggaggcucgcgaucgcgaagccgagaaacuucacuccc
.<<<<<<<<..<<<<<<<<..>>>>.>>>>......>>>>>>>>..
Receptor-Ligand Complex Structure
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PDB
2vpl
Domain II of Thermus thermophilus ribosomal protein L1 hinders recognition of its mRNA.
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
H3 G4 K5 R6 Y7 A35 K36 F37 T40 E42 H44 K46 D166 T168 H172 P174 S211 Y213 T217 M218 G219 S221
Binding residue
(residue number reindexed from 1)
H3 G4 K5 R6 Y7 A35 K36 F37 T40 E42 H44 K46 D75 T77 H81 P83 S120 Y122 T126 M127 G128 S130
Binding affinity
PDBbind-CN
: Kd=45.4nM
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:2vpl
,
PDBe:2vpl
,
PDBj:2vpl
PDBsum
2vpl
PubMed
18778715
UniProt
P27150
|RL1_THETH Large ribosomal subunit protein uL1 (Gene Name=rplA)
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