Structure of PDB 2vir Chain C Binding Site BS01

Receptor Information
>2vir Chain C (length=267) Species: 132504 (Influenza A virus (A/X-31(H3N2))) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VQSSSTGKICNNPHRILDGIDCTLIDALLGDPHCDVFQDETWDLFVERSK
AFSNCYPYDVPDYASLRSLVASSGTLEFITEGFTWTGVTQNGGSNACKRG
PGSGFFSRLNWLTKSGSTYPVLDVTMPNNDNFDKLYIWGIHHPSTNQEQT
SLYVQASGRVTVSTRRSQQTIIPNIGSRPWVRGLSSRISIYWTIVKPGDV
LVINSNGNLIAPRGYFKMRTGKSSIMRSDAPIDTCISECITPDGSIPNDK
PFQNVNKITYGACPKYV
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2vir Chain C Residue 1 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2vir Antigen distortion allows influenza virus to escape neutralization.
Resolution3.25 Å
Binding residue
(original residue number in PDB)		H56 E280
Binding residue
(residue number reindexed from 1)		H14 E238
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0046789 host cell surface receptor binding
Biological Process
GO:0019064 fusion of virus membrane with host plasma membrane
Cellular Component
GO:0019031 viral envelope

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2vir, PDBe:2vir, PDBj:2vir
PDBsum2vir
PubMed9461077
UniProtP03437|HEMA_I68A0 Hemagglutinin (Gene Name=HA)

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