Structure of PDB 2v3c Chain C Binding Site BS01

Receptor Information
>2v3c Chain C (length=403) Species: 2190 (Methanocaldococcus jannaschii) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MDKLGENLNKALNKLKAAAFVDKKLIKEVIKDIQRALIQADVNVKLVLKM
SKEIERRALEEKTPKGLSKKEHIIKIVYEELVKLLGEEAKKLELNPKKQN
VILLVGIQGSGKTTTAAKLARYIQKRGLKPALIAADTYRPAAYEQLKQLA
EKIHVPIYGDETRTKSPVDIVKEGMEKFKKADVLIIDTAGRHKEEKGLLE
EMKQIKEITNPDEIILVIDGTIGQQAGIQAKAFKEAVGEIGSIIVTKLDG
SAKGGGALSAVAETKAPIKFIGIGEGIDDLEPFDPKKFISRLLGMGDLES
LLEKAEDMVDEKTEESIDAIMRGKFTLNELMTQLEAIENMLTEAKIKKYK
VIISSMTKEERENPKIIKASRIRRIARGSGTTENDVREVLRYYETTKNAI
DKL
Ligand information
>2v3c Chain M (length=96) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ggcggugggggagcaucuccuguaggggagauguaacccccuuuaccugc
cgaaccccgccaggcccggaagggagcaacgguaggcaggacgucg
.<<<..<<<<<.<<<<<<<<<....>>>>>>>>>..>>>>>....<<<<<
<.....<<<...<.<<<....>>>..>..>>>..>>>>>>.>>>..
Receptor-Ligand Complex Structure
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PDB2v3c Interaction of Signal-Recognition Particle 54 Gtpase Domain and Signal-Recognition Particle RNA in the Free Signal-Recognition Particle.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		K17 K71 E72 K126 K130 E300 S301 E304 K371 V375 S378 S379 M380 T381 K382 R385 S394 R395 R398 G402 S403 G404
Binding residue
(residue number reindexed from 1)		K16 K70 E71 K125 K129 E299 S300 E303 K347 V351 S354 S355 M356 T357 K358 R361 S370 R371 R374 G378 S379 G380
Enzymatic activity
Enzyme Commision number 3.6.5.4: signal-recognition-particle GTPase.
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003924 GTPase activity
GO:0005525 GTP binding
GO:0008312 7S RNA binding
GO:0016787 hydrolase activity
GO:0016887 ATP hydrolysis activity
GO:0060090 molecular adaptor activity
Biological Process
GO:0006612 protein targeting to membrane
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
Cellular Component
GO:0005737 cytoplasm
GO:0048500 signal recognition particle

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2v3c, PDBe:2v3c, PDBj:2v3c
PDBsum2v3c
PubMed17846429
UniProtQ57565|SRP54_METJA Signal recognition particle 54 kDa protein (Gene Name=srp54)

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