Structure of PDB 2uzp Chain C Binding Site BS01
Receptor Information
>2uzp Chain C (length=142) Species:
9606
(Homo sapiens) [
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SMHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLI
PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTS
RNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADA
Ligand information
Ligand ID
PLP
InChI
InChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKey
NGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
Software
SMILES
CACTVS 3.341
Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0
Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04
O=P(O)(O)OCc1cnc(c(O)c1C=O)C
Formula
C8 H10 N O6 P
Name
PYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBL
CHEMBL82202
DrugBank
DB00114
ZINC
ZINC000001532514
PDB chain
2uzp Chain C Residue 1294 [
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Receptor-Ligand Complex Structure
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PDB
2uzp
Crystal Structure of C2 Domain of Protein Kinase C Gamma
Resolution
2.0 Å
Binding residue
(original residue number in PDB)
S-1 H154 A291
Binding residue
(residue number reindexed from 1)
S1 H3 A140
Annotation score
1
Enzymatic activity
Enzyme Commision number
2.7.11.13
: protein kinase C.
External links
PDB
RCSB:2uzp
,
PDBe:2uzp
,
PDBj:2uzp
PDBsum
2uzp
PubMed
UniProt
P05129
|KPCG_HUMAN Protein kinase C gamma type (Gene Name=PRKCG)
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