Structure of PDB 2uzp Chain C Binding Site BS01

Receptor Information
>2uzp Chain C (length=142) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SMHTERRGRLQLEIRAPTADEIHVTVGEARNLIPMDPNGLSDPYVKLKLI
PDPRNLTKQKTRTVKATLNPVWNETFVFNLKPGDVERRLSVEVWDWDRTS
RNDFMGAMSFGVSELLKAPVDGWYKLLNQEEGEYYNVPVADA
Ligand information
Ligand IDPLP
InChIInChI=1S/C8H10NO6P/c1-5-8(11)7(3-10)6(2-9-5)4-15-16(12,13)14/h2-3,11H,4H2,1H3,(H2,12,13,14)
InChIKeyNGVDGCNFYWLIFO-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341Cc1ncc(CO[P](O)(O)=O)c(C=O)c1O
OpenEye OEToolkits 1.5.0Cc1c(c(c(cn1)COP(=O)(O)O)C=O)O
ACDLabs 10.04O=P(O)(O)OCc1cnc(c(O)c1C=O)C
FormulaC8 H10 N O6 P
NamePYRIDOXAL-5'-PHOSPHATE;
VITAMIN B6 Phosphate
ChEMBLCHEMBL82202
DrugBankDB00114
ZINCZINC000001532514
PDB chain2uzp Chain C Residue 1294 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2uzp Crystal Structure of C2 Domain of Protein Kinase C Gamma
Resolution2.0 Å
Binding residue
(original residue number in PDB)
S-1 H154 A291
Binding residue
(residue number reindexed from 1)
S1 H3 A140
Annotation score1
Enzymatic activity
Enzyme Commision number 2.7.11.13: protein kinase C.
External links
PDB RCSB:2uzp, PDBe:2uzp, PDBj:2uzp
PDBsum2uzp
PubMed
UniProtP05129|KPCG_HUMAN Protein kinase C gamma type (Gene Name=PRKCG)

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