Structure of PDB 2opz Chain C Binding Site BS01
Receptor Information
>2opz Chain C (length=109) Species:
9606
(Homo sapiens) [
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NFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKV
KCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSL
EECLVRTTE
Ligand information
>2opz Chain G (length=4) [
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AVPF
Receptor-Ligand Complex Structure
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PDB
2opz
Structure-activity based study of the Smac-binding pocket within the BIR3 domain of XIAP.
Resolution
3.0 Å
Binding residue
(original residue number in PDB)
L292 K297 V298 G306 L307 T308 E314 Q319 W323
Binding residue
(residue number reindexed from 1)
L44 K49 V50 G58 L59 T60 E66 Q71 W75
Enzymatic activity
Enzyme Commision number
2.3.2.27
: RING-type E3 ubiquitin transferase.
External links
PDB
RCSB:2opz
,
PDBe:2opz
,
PDBj:2opz
PDBsum
2opz
PubMed
17336535
UniProt
P98170
|XIAP_HUMAN E3 ubiquitin-protein ligase XIAP (Gene Name=XIAP)
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