Structure of PDB 2j2p Chain C Binding Site BS01

Receptor Information
>2j2p Chain C (length=212) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
PRTCKDLLDRGHFLSGWHTIYLPDCRPLTVLCDMDTDGGGWTVFQRRVDG
SVDFYRDWATYKQGFGSRLGEFWLGNDNIHALTAQGTSELRTDLVDFEDN
YQFAKYRSFKVADEAEKYNLVLGAFVEGSAGDSLTFHNNQSFSTKDQDND
LNTGNCAVMFQGAWWYKNCHTSNLNGRYLRGTHGSFANGINWKSGKGYNY
SYKVSEMKVRPA
Ligand information
Ligand IDSC2
InChIInChI=1S/C5H9NO3S/c1-3(7)6-4(2-10)5(8)9/h4,10H,2H2,1H3,(H,6,7)(H,8,9)/t4-/m0/s1
InChIKeyPWKSKIMOESPYIA-BYPYZUCNSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.0CC(=O)NC(CS)C(=O)O
ACDLabs 12.01O=C(NC(C(=O)O)CS)C
OpenEye OEToolkits 1.7.0CC(=O)N[C@@H](CS)C(=O)O
CACTVS 3.370CC(=O)N[C@@H](CS)C(O)=O
CACTVS 3.370CC(=O)N[CH](CS)C(O)=O
FormulaC5 H9 N O3 S
NameN-ACETYL-L-CYSTEINE;
(2R)-2-acetamido-3-sulfanyl-propanoic acid
ChEMBLCHEMBL600
DrugBankDB06151
ZINCZINC000003589203
PDB chain2j2p Chain C Residue 1289 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2j2p Structural Insights Into the Innate Immune Recognition Specificities of L- and H-Ficolins.
Resolution2.8 Å
Binding residue
(original residue number in PDB)		S127 S143 L145 G146
Binding residue
(residue number reindexed from 1)		S51 S67 L69 G70
Annotation score1
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:2j2p, PDBe:2j2p, PDBj:2j2p
PDBsum2j2p
PubMed17215869
UniProtQ15485|FCN2_HUMAN Ficolin-2 (Gene Name=FCN2)

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