Structure of PDB 2izo Chain C Binding Site BS01

Receptor Information
>2izo Chain C (length=244) Species: 2287 (Saccharolobus solfataricus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MFKIVYPNAKDFFSFINSITNVTDSIILNFTEDGIFSRHLTEDKVLMAIM
RIPKDVLSEYSIDSPTSVKLDVSSVKKILSKASKATIELTETDSGLKIII
RDGAKSTIYIKAEKGQVEQLTEPKVNLAVNFTTDESVLNVIAADVTLVGE
EMRISTEEDKIKIEAGEEGKRYVAFLMKDKPLKELSIDTSASSSYSAEMF
KDAVKGLRGFSAPTMVSFGENLPMKIDVEAVSGGHMIFWIAPRL
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain2izo Chain C Residue 1252 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2izo Structure of an Archaeal PCNA1-PCNA2-Fen1 Complex: Elucidating PCNA Subunit and Client Enzyme Specificity.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		E234 H240
Binding residue
(residue number reindexed from 1)		E229 H235
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0030337 DNA polymerase processivity factor activity
Biological Process
GO:0006260 DNA replication
GO:0006272 leading strand elongation
GO:0006275 regulation of DNA replication

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Molecular Function
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Biological Process
External links
PDB RCSB:2izo, PDBe:2izo, PDBj:2izo
PDBsum2izo
PubMed16945955
UniProtP57766|PCNA1_SACS2 DNA polymerase sliding clamp 1 (Gene Name=pcn1)

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