Structure of PDB 2hnt Chain C Binding Site BS01

Receptor Information
>2hnt Chain C (length=67) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
IVEGSDAEIGMSPWQVMLFRKSPQELLCGASLISDRWVLTAAHCLLYPPW
DKNFTENDLLVRIGKHS
Ligand information
>2hnt Chain L (length=28) Species: 9606 (Homo sapiens) [Search peptide sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
ADCGLRPLFEKKSLEDKTERELLESYID
Receptor-Ligand Complex Structure
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PDB2hnt Crystallographic structure of human gamma-thrombin.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		S20 E23 I24 G25 M26 P28
Binding residue
(residue number reindexed from 1)		S5 E8 I9 G10 M11 P13
Enzymatic activity
Enzyme Commision number 3.4.21.5: thrombin.
Gene Ontology
Molecular Function
GO:0004252 serine-type endopeptidase activity
Biological Process
GO:0006508 proteolysis

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Molecular Function
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Biological Process
External links
PDB RCSB:2hnt, PDBe:2hnt, PDBj:2hnt
PDBsum2hnt
PubMed8071320
UniProtP00734|THRB_HUMAN Prothrombin (Gene Name=F2)

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