Structure of PDB 2hfe Chain C Binding Site BS01

Receptor Information
>2hfe Chain C (length=57) Species: 32630 (synthetic construct) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SALHWRAAGAATVLLVIVLLAGSYLAVLAERGAPGAQLITYPRALWWACE
TATTVGY
Ligand information
Ligand IDGOA
InChIInChI=1S/C2H4O3/c3-1-2(4)5/h3H,1H2,(H,4,5)
InChIKeyAEMRFAOFKBGASW-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 12.01O=C(O)CO
OpenEye OEToolkits 1.7.0C(C(=O)O)O
CACTVS 3.370OCC(O)=O
FormulaC2 H4 O3
NameGLYCOLIC ACID;
HYDROXYACETIC ACID;
HYDROXYETHANOIC ACID
ChEMBLCHEMBL252557
DrugBankDB03085
ZINCZINC000004658557
PDB chain2hfe Chain C Residue 79 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2hfe Structural and Functional Consequences of an Amide-to-Ester Substitution in the Selectivity Filter of a Potassium Channel.
Resolution2.25 Å
Binding residue
(original residue number in PDB)		G77 Y78
Binding residue
(residue number reindexed from 1)		G56 Y57
Annotation score1
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005249 voltage-gated potassium channel activity
Biological Process
GO:0006813 potassium ion transport
Cellular Component
GO:0008076 voltage-gated potassium channel complex

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Biological Process
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Cellular Component
External links
PDB RCSB:2hfe, PDBe:2hfe, PDBj:2hfe
PDBsum2hfe
PubMed16939283
UniProtP0A333|KCSA_STRCO pH-gated potassium channel KcsA (Gene Name=kcsA)

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