Structure of PDB 2flh Chain C Binding Site BS01

Receptor Information
>2flh Chain C (length=152) Species: 157791 (Vigna radiata) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MVKEFNTQTELSVRLEALWAVLSKDFITVVPKVLPHIVKDVQLIEGDGGV
GTILIFNFLPEVSPSYQREEITEFDESSHEIGLQVIEGGYLSQGLSYYKT
TFKLSEIEEDKTLVNVKISYDHDSDIEEKVTPTKTSQSTLMYLRRLERYL
SN
Ligand information
Ligand IDZEA
InChIInChI=1S/C10H13N5O/c1-7(4-16)2-3-11-9-8-10(13-5-12-8)15-6-14-9/h2,5-6,16H,3-4H2,1H3,(H2,11,12,13,14,15)/b7-2+
InChIKeyUZKQTCBAMSWPJD-FARCUNLSSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.5CC(=CCNc1c2c([nH]cn2)ncn1)CO
OpenEye OEToolkits 1.7.5C/C(=C\CNc1c2c([nH]cn2)ncn1)/CO
CACTVS 3.385CC(/CO)=C\CNc1ncnc2[nH]cnc12
CACTVS 3.385CC(CO)=CCNc1ncnc2[nH]cnc12
ACDLabs 10.04n2c1c(ncn1)c(nc2)NC\C=C(/C)CO
FormulaC10 H13 N5 O
Name(2E)-2-methyl-4-(9H-purin-6-ylamino)but-2-en-1-ol;
TRANS-ZEATIN
ChEMBLCHEMBL525239
DrugBankDB11337
ZINCZINC000004492895
PDB chain2flh Chain C Residue 705 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2flh Crystal Structure of Vigna radiata Cytokinin-Specific Binding Protein in Complex with Zeatin.
Resolution1.2 Å
Binding residue
(original residue number in PDB)		L22 F26 Q67 E69 L83 F102 T139
Binding residue
(residue number reindexed from 1)		L22 F26 Q67 E69 L83 F102 T139
Annotation score4
Binding affinityMOAD: Kd=106uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0004864 protein phosphatase inhibitor activity
GO:0010331 gibberellin binding
GO:0010427 abscisic acid binding
GO:0038023 signaling receptor activity
GO:0044373 cytokinin binding
Biological Process
GO:0006952 defense response
GO:0009738 abscisic acid-activated signaling pathway
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:2flh, PDBe:2flh, PDBj:2flh
PDBsum2flh
PubMed16998071
UniProtA0A1S3THR8|PHBP_VIGRR Phytohormone-binding protein CSBP (Gene Name=CSBP)

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