Structure of PDB 2f5w Chain C Binding Site BS01

Receptor Information
>2f5w Chain C (length=108) Species: 1390 (Bacillus amyloliquefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VINTFDGVADYLQTYHKLPDNYITKSEAQALGWVASKGNLADVAPGKSIG
GDIFSNREGKLPGKSGRTWREADINYTSGFRNSDRILYSSDWLIYKTTDH
YQTFTKIR
Ligand information
Ligand IDTOU
InChIInChI=1S/CH4N2S/c2-1(3)4/h(H4,2,3,4)
InChIKeyUMGDCJDMYOKAJW-UHFFFAOYSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0C(=S)(N)N
CACTVS 3.341NC(N)=S
ACDLabs 10.04S=C(N)N
FormulaC H4 N2 S
NameTHIOUREA
ChEMBLCHEMBL260876
DrugBank
ZINCZINC000008437745
PDB chain2f5w Chain C Residue 200 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2f5w On the edge of the denaturation process: Application of X-ray diffraction to barnase and lysozyme cross-linked crystals with denaturants in molar concentrations.
Resolution2.001 Å
Binding residue
(original residue number in PDB)		T103 F104
Binding residue
(residue number reindexed from 1)		T103 F104
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.27.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004521 RNA endonuclease activity
GO:0004540 RNA nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:2f5w, PDBe:2f5w, PDBj:2f5w
PDBsum2f5w
PubMed16600702
UniProtP00648|RNBR_BACAM Ribonuclease

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