Structure of PDB 2eqb Chain C Binding Site BS01

Receptor Information
>2eqb Chain C (length=93) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SNYNQLKEDYNTLKRELSDRDDEVKRLREDIAKENELRTKAEEEADKLNK
EVEDLTASLFDEANNMVADARKEKYAIEILNKRLTEQLREKDT
Ligand information
Ligand IDPO4
InChIInChI=1S/H3O4P/c1-5(2,3)4/h(H3,1,2,3,4)/p-3
InChIKeyNBIIXXVUZAFLBC-UHFFFAOYSA-K
SMILES
SoftwareSMILES
CACTVS 3.341[O-][P]([O-])([O-])=O
ACDLabs 10.04[O-]P([O-])([O-])=O
OpenEye OEToolkits 1.5.0[O-]P(=O)([O-])[O-]
FormulaO4 P
NamePHOSPHATE ION
ChEMBL
DrugBankDB14523
ZINC
PDB chain2eqb Chain C Residue 202 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2eqb Crystal structure of the Sec4p{middle dot}Sec2p complex in the nucleotide exchanging intermediate state
Resolution2.7 Å
Binding residue
(original residue number in PDB)		R120 K123
Binding residue
(residue number reindexed from 1)		R71 K74
Annotation score3
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005085 guanyl-nucleotide exchange factor activity

View graph for
Molecular Function
External links
PDB RCSB:2eqb, PDBe:2eqb, PDBj:2eqb
PDBsum2eqb
PubMed17488829
UniProtP17065|SEC2_YEAST Rab guanine nucleotide exchange factor SEC2 (Gene Name=SEC2)

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