Structure of PDB 2ce8 Chain C Binding Site BS01

Receptor Information
>2ce8 Chain C (length=337) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DYFQGAMGSKPAYSFHVTADGQMQPVPFPPDALIGPGIPRHARQINTLNH
GEVVCAVTISNPTRHVYTGGKGCVKVWDISHPGNKSPVSQLDCLNRDNYI
RSCKLLPDGCTLIVGGEASTLSIWDLAAPTPRIKAELTSSAPACYALAIS
PDSKVCFSCCSDGNIAVWDLHNQTLVRQFQGHTDGASCIDISNDGTKLWT
GGLDNTVRSWDLREGRQLQQHDFTSQIFSLGYCPTGEWLAVGMESSNVEV
LHVNKPDKYQLHLHESCVLSLKFAYCGKWFVSTGKDNLLNAWRTPYGASI
FQSKESSSVLSCDISVDDKYIVTGSGDKKATVYEVIY
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB2ce8 Molecular Recognition of Transcriptional Repressor Motifs by the Wd Domain of the Groucho/Tle Corepressor.
Resolution2.03 Å
Binding residue
(original residue number in PDB)		V486 C488 Y532 R534 E550 Y578 S594 D617 L636 F661
Binding residue
(residue number reindexed from 1)		V53 C55 Y99 R101 E117 Y145 S161 D184 L203 F228
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Biological Process
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005634 nucleus

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Biological Process
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Cellular Component
External links
PDB RCSB:2ce8, PDBe:2ce8, PDBj:2ce8
PDBsum2ce8
PubMed16762837
UniProtQ04724|TLE1_HUMAN Transducin-like enhancer protein 1 (Gene Name=TLE1)

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