Structure of PDB 2cax Chain C Binding Site BS01

Receptor Information

>2cax Chain C (length=53) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MAKKDIMGDKTVRVRADLHHIIKIETAKNGGNVKEVMDQALEEYIRKYLP
DKL

Ligand information

>2cax Chain U (length=18) [Search DNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

gaatcacaagtcacaagc

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	2cax Structures of Omega Repressors Bound to Direct and Inverted DNA Repeats Explain Modulation of Transcription.
Resolution	2.9 Å
Binding residue (original residue number in PDB)	K41 N50 V51 K52
Binding residue (residue number reindexed from 1)	K23 N32 V33 K34
Binding affinity	PDBbind-CN: Kd=40nM

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006355	regulation of DNA-templated transcription

View graph for
Biological Process

External links

PDB	RCSB:2cax, PDBe:2cax, PDBj:2cax
PDBsum	2cax
PubMed	16528102
UniProt	Q57468

[Back to BioLiP]