Structure of PDB 2bl0 Chain C Binding Site BS01

Receptor Information
>2bl0 Chain C (length=142) Species: 5791 (Physarum polycephalum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GDDQVSEFKEAFELFDSERTGFITKEGLQTVLKQFGVRVEPAAFNEMFNE
ADATGNGKIQFPEFLSMMGRRMKQTTSEDILRQAFRTFDPEGTGYIPKAA
LQDALLNLGDRLKPHEFAEFLGITETEKGQIRYDNFINTMFT
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain2bl0 Chain C Residue 1155 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB2bl0 Structural Evidence for Non-Canonical Binding of Ca2+ to a Canonical EF-Hand of a Conventional Myosin.
Resolution1.75 Å
Binding residue
(original residue number in PDB)		D64 T66 N68 K70 E75
Binding residue
(residue number reindexed from 1)		D52 T54 N56 K58 E63
Annotation score4
Enzymatic activity
Enzyme Commision number 3.6.1.32: Transferred entry: 5.6.1.8.
Gene Ontology
Molecular Function
GO:0005509 calcium ion binding
GO:0032036 myosin heavy chain binding
GO:0046872 metal ion binding
Cellular Component
GO:0005737 cytoplasm
GO:0016460 myosin II complex

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Molecular Function
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Cellular Component
External links
PDB RCSB:2bl0, PDBe:2bl0, PDBj:2bl0
PDBsum2bl0
PubMed16227209
UniProtQ8WSQ4

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