Structure of PDB 1z6r Chain C Binding Site BS01

Receptor Information
>1z6r Chain C (length=382) Species: 562 (Escherichia coli) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QIKQTNAGAVYRLIDQLGPVSRIDLSRLAQLAPASITKIVHEMLEAHLVQ
ELGLVVETEAWHYLSLRISRGEIFLALRDLSSKLVVEESQELALKDDLPL
LDRIISHIDQFFIRHQKKLERLTSIAITLPGIIDTENGIVHRMPFYEDVK
EMPLGEALEQHTGVPVYIQHDISAWTMAEALFGASRGARDVIQVVIDHNV
GAGVITDGHLLHAGSSSLVEIGHTQVDPYGKRCYCGNHGCLETIASVDSI
LELAQLRLNQSMSSMLHGQPLTVDSLCQAALRGDLLAKDIITGVGAHVGR
ILAIMVNLFNPQKILIGSPLSKAADILFPVISDSIRQQALPAYSQHISVE
STQFSNQGTMAGAALVKDAMYNGSLLIRLLQG
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1z6r Chain C Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1z6r The crystal structure of Mlc, a global regulator of sugar metabolism in Escherichia coli
Resolution2.7 Å
Binding residue
(original residue number in PDB)		H247 C257 C259 C264
Binding residue
(residue number reindexed from 1)		H223 C233 C235 C240
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0005515 protein binding
GO:0042802 identical protein binding
GO:0046872 metal ion binding
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription
Cellular Component
GO:0005737 cytoplasm
GO:0016020 membrane

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1z6r, PDBe:1z6r, PDBj:1z6r
PDBsum1z6r
PubMed15929984
UniProtP50456|MLC_ECOLI DNA-binding transcriptional repressor Mlc (Gene Name=mlc)

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