Structure of PDB 1yp4 Chain C Binding Site BS01

Receptor Information
>1yp4 Chain C (length=434) Species: 4113 (Solanum tuberosum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TCLDPDASRSVLGIILGGGAGTRLYPLTKKRAKPAVPLGANYRLIDIPVS
NCLNSNISKIYVLTQFNSASLNRHLSRAYASEGFVEVLAAQQSPENPDWF
QGTADAVRQYLWLFEEHTVLEYLILAGDHLYRMDYEKFIQAHRETDADIT
VAALPMDEKRATAFGLMKIDEEGRIIEFAEKPQGEQLQAMKVDTTILGLD
DKRAKEMPFIASMGIYVISKDVMLNLLRDKFPGANDFGSEVIPGATSLGM
RVQAYLYDGYWEDIGTIEAFYNANLGITKKPVPDFSFYDRSAPIYTQPRY
LPPSKMLDADVTDSVIGEGCVIKNCKIHHSVVGLRSCISEGAIIEDSLLM
GADYYETDADRKLLAAKGSVPIGIGKNCHIKRAIIDKNARIGDNVKIINK
DNVQEAARETDGYFIKSGIVTVIKDALIPSGIII
Ligand information
Ligand IDADP
InChIInChI=1S/C10H15N5O10P2/c11-8-5-9(13-2-12-8)15(3-14-5)10-7(17)6(16)4(24-10)1-23-27(21,22)25-26(18,19)20/h2-4,6-7,10,16-17H,1H2,(H,21,22)(H2,11,12,13)(H2,18,19,20)/t4-,6-,7-,10-/m1/s1
InChIKeyXTWYTFMLZFPYCI-KQYNXXCUSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N
CACTVS 3.341Nc1ncnc2n(cnc12)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 10.04O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c(ncnc12)N)C(O)C3O
CACTVS 3.341Nc1ncnc2n(cnc12)[C@@H]3O[C@H](CO[P@@](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
OpenEye OEToolkits 1.5.0c1nc(c2c(n1)n(cn2)C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N
FormulaC10 H15 N5 O10 P2
NameADENOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL14830
DrugBankDB16833
ZINCZINC000012360703
PDB chain1yp4 Chain C Residue 558 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1yp4 Crystal structure of potato tuber ADP-glucose pyrophosphorylase.
Resolution2.3 Å
Binding residue
(original residue number in PDB)		L26 G28 G29 Q118 T120 A143 D145 S256
Binding residue
(residue number reindexed from 1)		L16 G18 G19 Q101 T103 A126 D128 S239
Annotation score4
Enzymatic activity
Enzyme Commision number 2.7.7.27: glucose-1-phosphate adenylyltransferase.
Gene Ontology
Molecular Function
GO:0008878 glucose-1-phosphate adenylyltransferase activity
Biological Process
GO:0005978 glycogen biosynthetic process
GO:0009058 biosynthetic process

View graph for
Molecular Function
View graph for
Biological Process
External links
PDB RCSB:1yp4, PDBe:1yp4, PDBj:1yp4
PDBsum1yp4
PubMed15692569
UniProtP23509|GLGS_SOLTU Glucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic

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