Structure of PDB 1y2a Chain C Binding Site BS01
Receptor Information
>1y2a Chain C (length=423) Species:
10090
(Mus musculus) [
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NWSVEDIVKGINSNNLESQLQATQAARKLLSREKQPPIDNIIRAGLIPKF
VSFLGKTDCSPIQFESAWALTNIASGTSEQTKAVVDGGAIPAFISLLASP
HAHISEQAVWALGNIAGDGSAFRDLVIKHGAIDPLLALLAVPDLSTLACG
YLRNLTWTLSNLCRNKNPAPPLDAVEQILPTLVRLLHHNDPEVLADSCWA
ISYLTDGPNERIEMVVKKGVVPQLVKLLGATELPIVTPALRAIGNIVTGT
DEQTQKVIDAGALAVFPSLLTNPKTNIQKEATWTMSNITAGRQDQIQQVV
NHGLVPFLVGVLSKADFKTQKEAAWAITNYTSGGTVEQIVYLVHCGIIEP
LMNLLSAKDTKIIQVILDAISNIFQAAEKLGETEKLSIMIEECGGLDKIE
ALQRHENESVYKASLNLIEKYFS
Ligand information
>1y2a Chain P (length=10) Species:
9606
(Homo sapiens) [
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GKISKHWTGI
Receptor-Ligand Complex Structure
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PDB
1y2a
Phospholipid Scramblase 1 Contains a Nonclassical Nuclear Localization Signal with Unique Binding Site in Importin alpha
Resolution
2.2 Å
Binding residue
(original residue number in PDB)
Q98 R101 K102 S105 W142 N146 S149 G150 T155 Q181 W184 N188 D192 W231 R238
Binding residue
(residue number reindexed from 1)
Q24 R27 K28 S31 W68 N72 S75 G76 T81 Q107 W110 N114 D118 W157 R164
Enzymatic activity
Enzyme Commision number
?
External links
PDB
RCSB:1y2a
,
PDBe:1y2a
,
PDBj:1y2a
PDBsum
1y2a
PubMed
15611084
UniProt
P52293
|IMA1_MOUSE Importin subunit alpha-1 (Gene Name=Kpna2)
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