Structure of PDB 1uup Chain C Binding Site BS01

Receptor Information
>1uup Chain C (length=221) Species: 1314 (Streptococcus pyogenes) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QQDPDPSQLHRSSLVKNLQNIYFLYEGDPVTHENVKSVDQLLSHDLIYNV
SGPNYDKLKTELKNQEMATLFKDKNVDIYGVEYYHLCYLCENAERSACIY
GGVTNHEGNHLEIPKKIVVKVSIDGIQSLSFDIETNKKMVTAQELDYKVR
KYLTDNKQLYTNGPSKYETGYIKFIPKNKESFWFDFFPEPEFTQSKYLMI
YKDNETLDSNTSQIEVYLTTK
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1uup Chain C Residue 4222 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1uup Crystal Structure of a Dimeric Form of Streptococcal Pyrogenic Exotoxin a (Spea1)
Resolution2.6 Å
Binding residue
(original residue number in PDB)		E3033 D3077 H3106 H3110
Binding residue
(residue number reindexed from 1)		E33 D77 H106 H110
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005576 extracellular region

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Molecular Function
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Cellular Component
External links
PDB RCSB:1uup, PDBe:1uup, PDBj:1uup
PDBsum1uup
PubMed15295110
UniProtP0DJY7|SPEA_STRPY Exotoxin type A (Gene Name=speA)

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