Structure of PDB 1u7p Chain C Binding Site BS01

Receptor Information
>1u7p Chain C (length=163) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
TRLPKLAVFDLDYTLWPFWVDTHVDPPFHKSSDGTVRDRRGQNIQLYPEV
PEVLGRLQSLGVPVAAASRTSEIQGANQLLELFDLGKYFIQREIYPGSKV
THFERLHHKTGVPFSQMVFFDDENRNIIDVGRLGVTCIHIRDGMSLQTLT
QGLETFAKAQAGL
Ligand information
Ligand IDMG
InChIInChI=1S/Mg/q+2
InChIKeyJLVVSXFLKOJNIY-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Mg+2]
CACTVS 3.341[Mg++]
FormulaMg
NameMAGNESIUM ION
ChEMBL
DrugBankDB01378
ZINC
PDB chain1u7p Chain C Residue 503 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1u7p X-ray Crystal Structure of the Hypothetical Phosphotyrosine Phosphatase MDP-1 of the Haloacid Dehalogenase Superfamily
Resolution1.9 Å
Binding residue
(original residue number in PDB)		D11 D13 D123
Binding residue
(residue number reindexed from 1)		D10 D12 D122
Annotation score1
Enzymatic activity
Enzyme Commision number 3.1.3.-
3.1.3.48: protein-tyrosine-phosphatase.
Gene Ontology
Molecular Function
GO:0004721 phosphoprotein phosphatase activity
GO:0004725 protein tyrosine phosphatase activity
GO:0016791 phosphatase activity
GO:0046872 metal ion binding

View graph for
Molecular Function
External links
PDB RCSB:1u7p, PDBe:1u7p, PDBj:1u7p
PDBsum1u7p
PubMed15461449
UniProtQ9D967|MGDP1_MOUSE Magnesium-dependent phosphatase 1 (Gene Name=Mdp1)

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