Structure of PDB 1tx3 Chain C Binding Site BS01

Receptor Information
>1tx3 Chain C (length=255) Species: 727 (Haemophilus influenzae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SFIKPIYQDINSILIGQKVKRPKSGTLSGHAAGEPFEKLVYKFLKENLSD
LTFKQYEYLNDLFMKNPAIIGHEARYKLFNSPTLLFLLSRGKAATENWSI
ENLFEEKQNDTADILLVKQFYELLDVKTRNISKSAQAPNIISAYKLAQTC
AKMIDNKEFDLFDINYLEVDWELNGEDLVCVSTSFAELFKSEPSELYINW
AAAMQIQFHVRDLDQGFNGTREEWAKSYLKHFVTQAEQRAISMIDKFVKP
FKKYI
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1tx3 Ca2+ binding in the active site of HincII: implications for the catalytic mechanism
Resolution2.5 Å
Binding residue
(original residue number in PDB)		Y77 G92 K93 Q109 Q138 Y199 N201 A203 A204 K248
Binding residue
(residue number reindexed from 1)		Y76 G91 K92 Q108 Q136 Y197 N199 A201 A202 K246
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0003677 DNA binding
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1tx3, PDBe:1tx3, PDBj:1tx3
PDBsum1tx3
PubMed15491133
UniProtP17743|T2C2_HAEIF Type II restriction enzyme HincII (Gene Name=hincIIR)

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