Structure of PDB 1swi Chain C Binding Site BS01

Receptor Information
>1swi Chain C (length=30) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RMKQLEDKVEELLSKAYHLENEVARLKKLV
Ligand information
Ligand IDBNZ
InChIInChI=1S/C6H6/c1-2-4-6-5-3-1/h1-6H
InChIKeyUHOVQNZJYSORNB-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 11.02
CACTVS 3.352
OpenEye OEToolkits 1.7.0		c1ccccc1
FormulaC6 H6
NameBENZENE
ChEMBLCHEMBL277500
DrugBank
ZINCZINC000000967532
PDB chain1swi Chain B Residue 100 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1swi An engineered allosteric switch in leucine-zipper oligomerization.
Resolution2.6 Å
Binding residue
(original residue number in PDB)		L12 A16
Binding residue
(residue number reindexed from 1)		L12 A16
Annotation score1
Binding affinityPDBbind-CN: -logKd/Ki=3.10,Kd=800uM
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006355 regulation of DNA-templated transcription

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Molecular Function
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Biological Process
External links
PDB RCSB:1swi, PDBe:1swi, PDBj:1swi
PDBsum1swi
PubMed8646536
UniProtP03069|GCN4_YEAST General control transcription factor GCN4 (Gene Name=GCN4)

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