Structure of PDB 1pz8 Chain C Binding Site BS01

Receptor Information
>1pz8 Chain C (length=176) Species: 9031 (Gallus gallus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AEAIAFDGRTYMEYHNAVEKALQSNHFELSIKTEATQGLILWSGKGLERS
DYIALAIVDGFVQMMYDLGSKPVVLRSTVPINTNHWTHIKAYRVQREGSL
QVGNEAPITGSSPLGATQLDTDGALWLGGMERLSVAHKLPKAYSTGFIGC
IRDVIVDRQELHLVEDALNNPTILHC
Ligand information
Ligand IDCA
InChIInChI=1S/Ca/q+2
InChIKeyBHPQYMZQTOCNFJ-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Ca++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Ca+2]
FormulaCa
NameCALCIUM ION
ChEMBL
DrugBankDB14577
ZINC
PDB chain1pz8 Chain C Residue 703 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1pz8 Modulation of agrin function by alternative splicing and Ca2+ binding.
Resolution2.35 Å
Binding residue
(original residue number in PDB)		D73 L90 Q140 D142
Binding residue
(residue number reindexed from 1)		D51 L68 Q118 D120
Annotation score4
Enzymatic activity
Enzyme Commision number ?
External links
PDB RCSB:1pz8, PDBe:1pz8, PDBj:1pz8
PDBsum1pz8
PubMed15016366
UniProtP31696|AGRIN_CHICK Agrin (Gene Name=AGRN)

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