Structure of PDB 1pmp Chain C Binding Site BS01

Receptor Information

>1pmp Chain C (length=131) Species: 9913 (Bos taurus)

SNKFLGTWKLVSSENFDEYMKALGVGLATRKLGNLAKPRVIISKKGDIIT
IRTESPFKNTEISFKLGQEFEETTADNRKTKSTVTLARGSLNQVQKWNGN
ETTIKRKLVDGKMVVECKMKDVVCTRIYEKV

Ligand information

• Ligand ID: OLA
• InChI: InChI=1S/C18H34O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18(19)20/h9-10H,2-8,11-17H2,1H3,(H,19,20)/b10-9-
• InChIKey: ZQPPMHVWECSIRJ-KTKRTIGZSA-N
• SMILES:
  ACDLabs 10.04: O=C(O)CCCCCCC\C=C/CCCCCCCC
  CACTVS 3.341: CCCCCCCCC=CCCCCCCCC(O)=O
  CACTVS 3.341: CCCCCCCC\C=C/CCCCCCCC(O)=O
  OpenEye OEToolkits 1.5.0: CCCCCCCCC=CCCCCCCCC(=O)O
  OpenEye OEToolkits 1.5.0: CCCCCCCC\C=C/CCCCCCCC(=O)O
• Formula: C18 H34 O2
• Name: OLEIC ACID
• ChEMBL: CHEMBL8659
• ZINC: ZINC000006845860
• PDB chain: 1pmp Chain C Residue 200

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1pmp Crystallographic studies on a family of cellular lipophilic transport proteins. Refinement of P2 myelin protein and the structure determination and refinement of cellular retinol-binding protein in complex with all-trans-retinol.
• Resolution: 2.7 Å
• Binding residue (original residue number in PDB): F16 T29 R126 Y128
• Binding residue (residue number reindexed from 1): F16 T29 R126 Y128
• Annotation score: 3

Gene Ontology

Molecular Function

• GO:0005504 fatty acid binding
• GO:0008289 lipid binding
• GO:0015485 cholesterol binding

Biological Process

• GO:0015908 fatty acid transport
• GO:0061024 membrane organization

Cellular Component

• GO:0005634 nucleus
• GO:0005737 cytoplasm
• GO:0005829 cytosol
• GO:0043209 myelin sheath

External links

• PDB: RCSB:1pmp, PDBe:1pmp, PDBj:1pmp
• PDBsum: 1pmp
• PubMed: 7683727
• UniProt: P02690|MYP2_BOVIN Myelin P2 protein (Gene Name=PMP2)