Structure of PDB 1nwq Chain C Binding Site BS01

Receptor Information
>1nwq Chain C (length=60) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
NSNEYRVRRERNNIAVRKSRDKAKQRNVETQQKVLELTSDNDRLRKRVEQ
LSRELDTLRG
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]
PDB1nwq Structural Basis for DNA Recognition by the Basic Region Leucine Zipper Transcription Factor CCAAT/enhancer Binding Protein Alpha
Resolution2.8 Å
Binding residue
(original residue number in PDB)
Y285 R289 N292 N293 R297 R300
Binding residue
(residue number reindexed from 1)
Y5 R9 N12 N13 R17 R20
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003700 DNA-binding transcription factor activity
Biological Process
GO:0006351 DNA-templated transcription
GO:0006355 regulation of DNA-templated transcription

View graph for
Molecular Function

View graph for
Biological Process
External links
PDB RCSB:1nwq, PDBe:1nwq, PDBj:1nwq
PDBsum1nwq
PubMed12578822
UniProtP05554|CEBPA_RAT CCAAT/enhancer-binding protein alpha (Gene Name=Cebpa)

[Back to BioLiP]