Structure of PDB 1mzz Chain C Binding Site BS01

Receptor Information
>1mzz Chain C (length=334) Species: 1063 (Cereibacter sphaeroides) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VDLSNLPRVKHTLVPPPFAHAHEQVAASGPVINEFEMRIIEKEVQLDEDA
YLQAMTFDGSIPGPLMIVHEGDYVELTLINPPENTMPHNIDFHAATGALG
GGGLTLINPGEKVVLRFKATRAGAFVYHCAPGGPMIPWHVVSGTAGCIMV
LPRDGLKDHEGKPVRYDTVYYIGESDHYIPKDEDGTYMRFSDPSEGYEDM
VAVMDTLIPSHIVFNGAVGALTGEGALKAKVGDNVLFVHSQPNRDSRPHL
IGGHGDLVWETGKFHNAPERDLETWFIRGGTAGAALYKFLQPGVYAYVNH
NLIEAVHKGATAHVLVEGEWDNDLMEQVVAPVGL
Ligand information
Ligand IDCU
InChIInChI=1S/Cu/q+2
InChIKeyJPVYNHNXODAKFH-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Cu+2]
CACTVS 3.341[Cu++]
FormulaCu
NameCOPPER (II) ION
ChEMBL
DrugBankDB14552
ZINC
PDB chain1mzz Chain C Residue 2401 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1mzz The High resolution Crystal Structures of Nitrite Reductase and its mutant Met182Thr from Rhodobacter Sphaeroides Reveal a Gating Mechanism for the Electron Transfer to the Type 1 Copper Center
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H2126 C2167 H2177
Binding residue
(residue number reindexed from 1)		H88 C129 H139
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H2126 D2129 H2131 H2166 C2167 H2177 T2182 H2287 E2311 T2312 H2338
Catalytic site (residue number reindexed from 1) H88 D91 H93 H128 C129 H139 T144 H249 E273 T274 H300
Enzyme Commision number 1.7.2.1: nitrite reductase (NO-forming).
Gene Ontology
Molecular Function
GO:0005507 copper ion binding
GO:0016491 oxidoreductase activity
GO:0046872 metal ion binding
GO:0050421 nitrite reductase (NO-forming) activity
Biological Process
GO:0019333 denitrification pathway
GO:0042128 nitrate assimilation
Cellular Component
GO:0042597 periplasmic space

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1mzz, PDBe:1mzz, PDBj:1mzz
PDBsum1mzz
PubMed
UniProtQ53239|NIR_CERS5 Copper-containing nitrite reductase (Gene Name=nirK)

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