Structure of PDB 1m19 Chain C Binding Site BS01
Receptor Information
>1m19 Chain C (length=107) Species:
8355
(Xenopus laevis) [
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AKTRSSRAGLQFPVGRVHRLLRKGNYAERVGAGAPVYLAAVLEYLTAEIL
ELAGNAARDNKKTRIIPRHLQLAVRNDEELNKLLGRVTIAQGGVLPNIQS
VLLPKKT
Ligand information
>1m19 Chain I (length=146) [
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atcaatatccacctgcagattctaccaaaagtgtatttggaaactgctcc
atcaaaaggcatgttcagcggaattccgctgaacatgccttttgatggag
cagtttccaaatacacttttggtagaatctgcaggtggatattgat
Receptor-Ligand Complex Structure
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PDB
1m19
Crystal Structures of Nucleosome Core Particles in Complex with Minor Groove DNA-binding Ligands
Resolution
2.3 Å
Binding residue
(original residue number in PDB)
R817 G828 R832 R842 R877
Binding residue
(residue number reindexed from 1)
R4 G15 R19 R29 R64
Binding affinity
PDBbind-CN
: Kd=0.6uM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003677
DNA binding
GO:0030527
structural constituent of chromatin
GO:0046982
protein heterodimerization activity
Cellular Component
GO:0000786
nucleosome
GO:0005634
nucleus
GO:0005694
chromosome
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Molecular Function
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Cellular Component
External links
PDB
RCSB:1m19
,
PDBe:1m19
,
PDBj:1m19
PDBsum
1m19
PubMed
12559907
UniProt
P06897
|H2A1_XENLA Histone H2A type 1
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