Structure of PDB 1lw4 Chain C Binding Site BS01

Receptor Information

>1lw4 Chain C (length=343) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MIDLRSDTVTKPTEEMRKAMAQAEVGDDVYGEDPTINELERLAAETFGKE
AALFVPSGTMGNQVSIMAHTQRGDEVILEADSHIFWYEVGAMAVLSGVMP
HPVPGKNGAMDPDDVRKAIRPRNIHFPRTSLIAIENTHNRSGGRVVPLEN
IKEICTIAKEHGINVHIDGARIFNASIASGVPVKEYAGYADSVMFCLSKG
LCAPVGSVVVGDRDFIERARKARKMLGGGMRQAGVLAAAGIIALTKMVDR
LKEDHENARFLALKLKEIGYSVNPEDVKTNMVILRTDNLKVNAHGFIEAL
RNSGVLANAVSDTEIRLVTHKDVSRNDIEEALNIFEKLFRKFS

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1lw4 Chain B Residue 1057 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

Global view

Local view

Structure summary

[Spin on] [Spin off] [Reset]
[High quality] [Low quality]
[White background] [Black background]

PDB	1lw4 X-ray Structures of Threonine Aldolase Complexes: Structural Basis of Substrate Recognition
Resolution	1.9 Å
Binding residue (original residue number in PDB)	T8 T10 S198 A203
Binding residue (residue number reindexed from 1)	T8 T10 S198 A203
Annotation score	1

Enzymatic activity

Enzyme Commision number

4.1.2.5: L-threonine aldolase.

Gene Ontology

	Molecular Function
GO:0008732	L-allo-threonine aldolase activity
GO:0016829	lyase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006520	amino acid metabolic process
GO:0006545	glycine biosynthetic process
GO:0006567	threonine catabolic process

	Cellular Component
GO:0005829	cytosol

View graph for
Molecular Function

View graph for
Biological Process

View graph for
Cellular Component

External links

PDB	RCSB:1lw4, PDBe:1lw4, PDBj:1lw4
PDBsum	1lw4
PubMed	12269813
UniProt	Q9X266

[Back to BioLiP]