Structure of PDB 1knz Chain C Binding Site BS01
Receptor Information
>1knz Chain C (length=154) Species:
10923
(Simian rotavirus A/SA11) [
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TQQMAVSIINSSFEAAVVAATSALENMGIEYDYQDIYSRVKNKFDFVMDD
SGVKNNPIGKAITIDQALNNKFGSAIRNRNWLADTSRPAKLDEDVNKLRM
MLGIDQKMRVLNACFSVKRIPGKSSSIIKCTKLMRDKLERGEVEVDDSFV
DEKM
Ligand information
>1knz Chain X (length=5) [
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ugacc
.....
Receptor-Ligand Complex Structure
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PDB
1knz
Recognition of the rotavirus mRNA 3' consensus by an asymmetric NSP3 homodimer.
Resolution
2.45 Å
Binding residue
(original residue number in PDB)
N62 G65 K66 T69 S80 R83 N84 W87 R93 D100 G131 K132 S133 S134 S135
Binding residue
(residue number reindexed from 1)
N56 G59 K60 T63 S74 R77 N78 W81 R87 D94 G122 K123 S124 S125 S126
Binding affinity
PDBbind-CN
: Kd=79nM
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0003723
RNA binding
View graph for
Molecular Function
External links
PDB
RCSB:1knz
,
PDBe:1knz
,
PDBj:1knz
PDBsum
1knz
PubMed
11792322
UniProt
P03536
|NSP3_ROTS1 Non-structural protein 3
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