Structure of PDB 1jg8 Chain C Binding Site BS01

Receptor Information

>1jg8 Chain C (length=340) Species: 2336 (Thermotoga maritima) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

MIDLRSDTVTKPTEEMRKAMEVGDDVYGEDPTINELERLAAETFGKEAAL
FVPSGTMGNQVSIMAHTQRGDEVILEADSHIFWYEVGAMAVLSGVMPHPV
PGKNGAMDPDDVRKAIRPRNIHFPRTSLIAIENTHNRSGGRVVPLENIKE
ICTIAKEHGINVHIDGARIFNASIASGVPVKEYAGYADSVMFCLSKGLCA
PVGSVVVGDRDFIERARKARKMLGGGMRQAGVLAAAGIIALTKMVDRLKE
DHENARFLALKLKEIGYSVNPEDVKTNMVILRTDNLKVNAHGFIEALRNS
GVLANAVSDTEIRLVTHKDVSRNDIEEALNIFEKLFRKFS

Ligand information

Ligand ID

InChI

InChI=1S/Ca/q+2

InChIKey

BHPQYMZQTOCNFJ-UHFFFAOYSA-N

SMILES

Software	SMILES
CACTVS 3.341	[Ca++]
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Ca+2]

Formula

Name

CALCIUM ION

PDB chain

1jg8 Chain C Residue 904 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1jg8 Crystal Structure of Low-specificity Threonine Aldolase, a Key Enzyme in Glycine Biosynthesis
Resolution	1.8 Å
Binding residue (original residue number in PDB)	T12 T14 S202 A207
Binding residue (residue number reindexed from 1)	T8 T10 S195 A200
Annotation score	1

Enzymatic activity

Enzyme Commision number

4.1.2.5: L-threonine aldolase.

Gene Ontology

	Molecular Function
GO:0008732	L-allo-threonine aldolase activity
GO:0016829	lyase activity
GO:0046872	metal ion binding

	Biological Process
GO:0006520	amino acid metabolic process
GO:0006545	glycine biosynthetic process
GO:0006567	threonine catabolic process

	Cellular Component
GO:0005829	cytosol

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Molecular Function

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Cellular Component

External links

PDB	RCSB:1jg8, PDBe:1jg8, PDBj:1jg8
PDBsum	1jg8
PubMed
UniProt	Q9X266

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