Structure of PDB 1iru Chain C Binding Site BS01

Receptor Information

>1iru Chain C (length=250) Species: 9913 (Bos taurus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]

SRRYDSRTTIFSPEGRLYQVEYAMEAIGHAGTCLGILANDGVLLAAERRN
IHKLLDEVFFSEKIYKLNEDMACSVAGITSDANVLTNELRLIAQRYLLQY
QEPIPCEQLVTALCDIKQAYTQFGGKRPFGVSLLYIGWDKHYGFQLYQSD
PSGNYGGWKATCIGNNSAAAVSMLKQDYKEGEMTLKSALALAIKVLNKTM
DVSKLSAEKVEIATLTRENGKTVIRVLKQKEVEQLIKKHEEEEAKAEREK

Ligand information

Ligand ID

InChI

InChI=1S/Mg/q+2

InChIKey

JLVVSXFLKOJNIY-UHFFFAOYSA-N

SMILES

Software	SMILES
ACDLabs 10.04 OpenEye OEToolkits 1.5.0	[Mg+2]
CACTVS 3.341	[Mg++]

Formula

Name

MAGNESIUM ION

PDB chain

1iru Chain C Residue 314 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]

Receptor-Ligand Complex Structure

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Structure summary

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PDB	1iru The structure of the mammalian 20S proteasome at 2.75 A resolution.
Resolution	2.75 Å
Binding residue (original residue number in PDB)	G158 W159
Binding residue (residue number reindexed from 1)	G157 W158
Annotation score	4

Enzymatic activity

Enzyme Commision number

Gene Ontology

	Biological Process
GO:0006511	ubiquitin-dependent protein catabolic process
GO:0043161	proteasome-mediated ubiquitin-dependent protein catabolic process
GO:0051603	proteolysis involved in protein catabolic process

	Cellular Component
GO:0000502	proteasome complex
GO:0000932	P-body
GO:0005634	nucleus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005839	proteasome core complex
GO:0019773	proteasome core complex, alpha-subunit complex

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Biological Process

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Cellular Component

External links

PDB	RCSB:1iru, PDBe:1iru, PDBj:1iru
PDBsum	1iru
PubMed	12015144
UniProt	Q3ZCK9\|PSA4_BOVIN Proteasome subunit alpha type-4 (Gene Name=PSMA4)

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