Structure of PDB 1iqc Chain C Binding Site BS01

Receptor Information

>1iqc Chain C (length=308) Species: 915 (Nitrosomonas europaea)

ANEPIQPIKAVTPENADMAELGKMLFFDPRLSKSGFISCNSCHNLSMGGT
DNITTSIGHKWQQGPINAPTVLNSSMNLAQFWDGRAKDLKEQAAGPIANP
KEMASTHEIAEKVVASMPQYRERFKKVFGSDEVTIDRITTAIAQFEETLV
TPGSKFDKWLEGDKNALNQDELEGYNLFKGSGCVQCHNGPAVGGSSYQKM
GVFKPYETKNPAAGRMDVTGNEADRNVFKVPTLRNIELTYPYFHDGGAAT
LEQAVETMGRIQLNREFNKDEVSKIVAFLKTLTGDQPDFKLPILPPSNND
TPRSQPYE

Ligand information

• Ligand ID: CA
• InChI: InChI=1S/Ca/q+2
• InChIKey: BHPQYMZQTOCNFJ-UHFFFAOYSA-N
• SMILES:
  CACTVS 3.341: [Ca++]
  ACDLabs 10.04
  OpenEye OEToolkits 1.5.0: [Ca+2]
• Formula: Ca
• Name: CALCIUM ION
• DrugBank: DB14577
• PDB chain: 1iqc Chain C Residue 410

Receptor-Ligand Complex Structure

Structure summary

• PDB: 1iqc Crystal structure of Nitrosomonas europaea cytochrome c peroxidase and the structural basis for ligand switching in bacterial di-heme peroxidases
• Resolution: 1.8 Å
• Binding residue (original residue number in PDB): N67 T239 P241
• Binding residue (residue number reindexed from 1): N67 T239 P241
• Annotation score: 1

Enzymatic activity

• Catalytic site (original residue number in PDB): E102
• Catalytic site (residue number reindexed from 1): E102
• Enzyme Commision number: 1.11.1.5: cytochrome-c peroxidase.

Gene Ontology

Molecular Function

• GO:0004130 cytochrome-c peroxidase activity
• GO:0004601 peroxidase activity
• GO:0009055 electron transfer activity
• GO:0016491 oxidoreductase activity
• GO:0020037 heme binding
• GO:0046872 metal ion binding

Biological Process

• GO:0098869 cellular oxidant detoxification

Cellular Component

• GO:0042597 periplasmic space

External links

• PDB: RCSB:1iqc, PDBe:1iqc, PDBj:1iqc
• PDBsum: 1iqc
• PubMed: 11695895
• UniProt: P55929|CCPR_NITEU Cytochrome c551 peroxidase (Gene Name=ccp)