Structure of PDB 1i95 Chain C Binding Site BS01

Receptor Information
>1i95 Chain C (length=206) Species: 274 (Thermus thermophilus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GNKIHPIGFRLGITRDWESRWYAGKKQYRHLLLEDQRIRGLLEKELYSAG
LARVDIERAADNVAVTVHVAKPGVVIGRGGERIRVLREELAKLTGKNVAL
NVQEVQNPNLSAPLVAQRVAEQIERRFAVRRAIKQAVQRVMESGAKGAKV
IVSGRIGGAEQARTEWAAQGRVPLHTLRANIDYGFALARTTYGVLGVKAY
IFLGEV
Ligand information
>1i95 Chain A (length=1514) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
uguuggagaguuugauccuggcucagggugaacgcuggcggcgugccuaa
gacaugcaagucgugcgggccgcgggguuuuacuccguggucagcggcgg
acgggugaguaacgcgugggugaccuacccggaagagggggacaacccgg
ggaaacucgggcuaaucccccauguggacccgccccuuggggugugucca
aagggcuuugcccgcuuccggaugggcccgcgucccaucagcuaguuggu
gggguaauggcccaccaaggcgacgacggguagccggucugagaggaugg
ccggccacaggggcacugagacacgggccccacuccuacgggaggcagca
guuaggaaucuuccgcaaugggcgcaagccugacggagcgacgccgcuug
gaggaagaagcccuucgggguguaaacuccugaacccgggacgaaacccc
cgacgaggggacugacgguaccgggguaauagcgccggccaacuccgugc
cagcagccgcgguaauacggagggcgcgagcguuacccggauucacuggg
cguaaagggcguguaggcggccuggggcgucccaugugaaagaccacggc
ucaaccgugggggagcgugggauacgcucaggcuagacggugggagaggg
ugguggaauucccggaguagcggugaaaugcgcagauaccgggaggaacg
ccgauggcgaaggcagccaccugguccacccgugacgcugaggcgcgaaa
gcguggggagcaaaccggauuagauacccggguaguccacgcccuaaacg
augcgcgcuaggucucugggucuccugggggccgaagcuaacgcguuaag
cgcgccgccuggggaguacggccgcaaggcugaaacucaaaggaauugac
gggggcccgcacaagcgguggagcaugugguuuaauucgaagcaacgcga
agaaccuuaccaggccuugacaugcuagggaacccgggugaaagccuggg
gugccccgcgaggggagcccuagcacaggugcugcauggccgucgucagc
ucgugccgugagguguuggguuaagucccgcaacgagcgcaacccccgcc
guuaguugccagcgguucggccgggcacucuaacgggacugcccgcgaaa
gcgggaggaaggaggggacgacgucuggucagcauggcccuuacggccug
ggcgacacacgugcuacaaugcccacuacaaagcgaugccacccggcaac
ggggagcuaaucgcaaaaaggugggcccaguucggauuggggucugcaac
ccgaccccaugaagccggaaucgcuaguaaucgcggaucagccaugccgc
ggugaauacguucccgggccuuguacacaccgcccgucacgccaugggag
cgggcucuacccgaagucgccgggagccuacgggcaggcgccgaggguag
ggcccgugacuggggcgaagucguaacaagguagcuguaccggaaggugc
ggcuggaucaccuc
.......<<<<..[.((((.>>>>.<<<<.<<<<<..<<<<<<<...<..
<<<.<<<..<<<..<<.<<<<<<<<<<.....>>>>>>>>>>.>>>>>..
....<<.......<<<<<<<<..<<...<<<<<<<.<<<<<....<<<<<
......>>>>>.....>>>>>....<<<<.<<<<<....>>>>>.>>>>.
..<<<<...>>>>.>>>>>>>..>>>>>>>>>><<<....<<<..<<<<<
<<<.......>>>>>>>>>>>......>>>..<<<<<<<<....>>>>..
.>>>>.>>.<<<<<.<.........>>>>>>.<<<<....>>>>...>>>
>>>>........<<<....<<<<....>>>>..>>>...>.>>>>>>..<
<<<......<<<<....>>>>.....>>>>....<<<<<........<<<
<.....>>>>..........>>>>>......<<<<<(((...<<<<<...
..<<.)))>>.......>>>>>>>>>>..>>>>>>>>>..........<<
<((.....<<<<...<<<.<<<<<<<.<<<<<<<<<<......<<<<<<.
....>>>>>>....>>>>>>>>..>>>>>>>>>...<<<<<<<<...<<<
<<<<.<..<<<<<<<.<..<<<......>>>.....>.>>>>>>>...>.
......<<....>>.>>>>>>>..>>>>>.>>>...>>>...>>>>....
<<<<<<...<<...<<<<.........>>>>...>>>>>>>>........
..<<<<<<..<<<<<<<<<<...>>>>>>>>>>...<<..))>>.....>
>>>>>.>>>.<<<......<<<<....>>>>....>>>..)))).]<<<<
<.<<<<<<<.<<.<<<<<<..<<<<<<<<<<......<<........>>.
.........<<<<<<<......<<<<<<<<..<<<<<<<....>>>>>>>
...<<<......>>>..>>>>>>>>.<<<.<<<..<<<<<<.......<<
<<<<<<<....>>>..<<<<......>>>>..>>>>>>.....<<<<.<<
<<<<<..<<...<<<.....>>>.>>...>>>>>>>.....<<<<<....
>>>>>........>>>>.........>>>...>>>>>>>>>...>>>>>>
>...>>.>>>>>>>>.....<<<<<<<.....<<<..<<..<<<<....>
>>>..>>....>>>.....>>>>>>>......<....<<<<<<<......
..>>>>>>>....>.....>>>>>>....<<<<<<<..........>>>>
>>>......>>...>>>>>>>>>>.>>....<..<<.<.<<<<.<<<..<
<<<<<<<<<<<<...<.<<<<....<<<....>>>.>>>>.>..>>>>>>
>>>>>>>..>>>.>>>>..>.>>...>.....<<<<<<<<<....>>>>>
>>>>..........
Receptor-Ligand Complex Structure
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PDB1i95 Crystal structures of complexes of the small ribosomal subunit with tetracycline, edeine and IF3.
Resolution4.5 Å
Binding residue
(original residue number in PDB)		G2 R172 P174 T177 L178 G197
Binding residue
(residue number reindexed from 1)		G1 R171 P173 T176 L177 G196
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003676 nucleic acid binding
GO:0003723 RNA binding
GO:0003729 mRNA binding
GO:0003735 structural constituent of ribosome
GO:0019843 rRNA binding
Biological Process
GO:0006412 translation
Cellular Component
GO:0005840 ribosome
GO:0022627 cytosolic small ribosomal subunit
GO:1990904 ribonucleoprotein complex

View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1i95, PDBe:1i95, PDBj:1i95
PDBsum1i95
PubMed11296217
UniProtP80372|RS3_THET8 Small ribosomal subunit protein uS3 (Gene Name=rpsC)

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