Structure of PDB 1i7w Chain C Binding Site BS01

Receptor Information
>1i7w Chain C (length=509) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
QDDAELATRAIPELTKLLNDEDQVVVNKAAVMVHQLSKKEASRHAIMRSP
QMVSAIVRTMQNTNDVETARCTAGTLHNLSHHREGLLAIFKSGGIPALVK
MLGSPVDSVLFYAITTLHNLLLHQEGAKMAVRLAGGLQKMVALLNKTNVK
FLAITTDCLQILAYGNQESKLIILASGGPQALVNIMRTYTYEKLLWTTSR
VLKVLSVCSSNKPAIVEAGGMQALGLHLTDPSQRLVQNCLWTLRNLSDAA
TKQEGMEGLLGTLVQLLGSDDINVVTCAAGILSNLTCNNYKNKMMVCQVG
GIEALVRTVLRAGDREDITEPAICALRHLTSRHQEAEMAQNAVRLHYGLP
VVVKLLHPPSHWPLIKATVGLIRNLALCPANHAPLREQGAIPRLVQLLVR
AHQDTQRRTVRMEEIVEGCTGALHILARDVHNRIVIRGLNTIPLFVQLLY
SPIENIQRVAAGVLCELAQDKEAAEAIEAEGATAPLTELLHSRNEGVATY
AAAVLFRMS
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1i7w Chain C Residue 2 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1i7w The structure of the beta-catenin/E-cadherin complex and the molecular basis of diverse ligand recognition by beta-catenin.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		H176 C213
Binding residue
(residue number reindexed from 1)		H34 C71
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0045296 cadherin binding
Biological Process
GO:0007155 cell adhesion

View graph for
Molecular Function
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Biological Process
External links
PDB RCSB:1i7w, PDBe:1i7w, PDBj:1i7w
PDBsum1i7w
PubMed11348595
UniProtQ02248|CTNB1_MOUSE Catenin beta-1 (Gene Name=Ctnnb1)

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