Structure of PDB 1h65 Chain C Binding Site BS01

Receptor Information
>1h65 Chain C (length=256) Species: 3888 (Pisum sativum) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
VREWSGINTFAPATQTKLLELLGNLKQEDVNSLTILVMGKGGVGKSSTVN
SIIGERVVSISPFQSEGPRPVMVSRSRAGFTLNIIDTPGLIEGGYINDMA
LNIIKSFLLDKTIDVLLYVDRLDAYRVDNLDKLVAKAITDSFGKGIWNKA
IVALTHAQFSPPDGLPYDEFFSKRSEALLQVVRSGASLKKDAQASDIPVV
LIENSGRCNKNDSDEKVLPNGIAWIPHLVQTITEVALNKSESIFVDKNLI
DKLAAA
Ligand information
Ligand IDGDP
InChIInChI=1S/C10H15N5O11P2/c11-10-13-7-4(8(18)14-10)12-2-15(7)9-6(17)5(16)3(25-9)1-24-28(22,23)26-27(19,20)21/h2-3,5-6,9,16-17H,1H2,(H,22,23)(H2,19,20,21)(H3,11,13,14,18)/t3-,5-,6-,9-/m1/s1
InChIKeyQGWNDRXFNXRZMB-UUOKFMHZSA-N
SMILES
SoftwareSMILES
OpenEye OEToolkits 1.7.6c1nc2c(n1C3C(C(C(O3)COP(=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
CACTVS 3.385NC1=Nc2n(cnc2C(=O)N1)[C@@H]3O[C@H](CO[P](O)(=O)O[P](O)(O)=O)[C@@H](O)[C@H]3O
CACTVS 3.385NC1=Nc2n(cnc2C(=O)N1)[CH]3O[CH](CO[P](O)(=O)O[P](O)(O)=O)[CH](O)[CH]3O
ACDLabs 12.01O=P(O)(O)OP(=O)(O)OCC3OC(n2cnc1c2N=C(N)NC1=O)C(O)C3O
OpenEye OEToolkits 1.7.6c1nc2c(n1[C@H]3[C@@H]([C@@H]([C@H](O3)CO[P@](=O)(O)OP(=O)(O)O)O)O)N=C(NC2=O)N
FormulaC10 H15 N5 O11 P2
NameGUANOSINE-5'-DIPHOSPHATE
ChEMBLCHEMBL384759
DrugBankDB04315
ZINCZINC000008215481
PDB chain1h65 Chain B Residue 281 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1h65 Crystal Structure of Pea Toc34 - a Novel Gtpase of the Chloroplast Protein Translocon
Resolution2.0 Å
Binding residue
(original residue number in PDB)		Y132 P169
Binding residue
(residue number reindexed from 1)		Y125 P162
Annotation score4
Enzymatic activity
Enzyme Commision number 3.6.5.-
Gene Ontology
Molecular Function
GO:0005525 GTP binding
GO:0015450 protein-transporting ATPase activity
Biological Process
GO:0006886 intracellular protein transport
Cellular Component
GO:0009707 chloroplast outer membrane

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Molecular Function
View graph for
Biological Process
View graph for
Cellular Component
External links
PDB RCSB:1h65, PDBe:1h65, PDBj:1h65
PDBsum1h65
PubMed11753431
UniProtQ41009|TOC34_PEA Translocase of chloroplast 34 (Gene Name=TOC34)

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