Structure of PDB 1fzb Chain C Binding Site BS01

Receptor Information
>1fzb Chain C (length=309) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
KMLEEIMKYEASILTHDSSIRYLQEIYNSNNQKIVNLKEKVAQLEAQCQE
PCKDTVQIHDITGKDCQDIANKGAKQSGLYFIKPLKANQQFLVYCEIDGS
GNGWTVFQKRLDGSVDFKKNWIQYKEGFGHLSPTGTTEFWLGNEKIHLIS
TQSAIPYALRVELEDWNGRTSTADYAMFKVGPEADKYRLTYAYFAGGDAG
DAFDGFDFGDDPSDKFFTSHNGMQFSTWDNDNDKFEGNCAEQDGSGWWMN
KCHAGHLNGVYYQGGTYSKASTPNGYDNGIIWATWKTRWYSMKKTTMKII
PFNRLTIGE
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fzb Crystal structures of fragment D from human fibrinogen and its crosslinked counterpart from fibrin.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		D301 F322 Q329 K338 C339 H340 Y363 D364 R375
Binding residue
(residue number reindexed from 1)		D214 F235 Q242 K251 C252 H253 Y276 D277 R288
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding
Biological Process
GO:0007596 blood coagulation
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:1fzb, PDBe:1fzb, PDBj:1fzb
PDBsum1fzb
PubMed9333233
UniProtP02679|FIBG_HUMAN Fibrinogen gamma chain (Gene Name=FGG)

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