Structure of PDB 1fiu Chain C Binding Site BS01

Receptor Information
>1fiu Chain C (length=286) Species: 485 (Neisseria gonorrhoeae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
MQPLFTQERRIFHKKLLDGNILATNNRGVVSNADGSNTRSFNIAKGIADL
LHSETVSERLPGQTSGNAFEAICSEFVQSAFEKLQHIRPGDWNVKQVGSR
NRLEIARYQQYAHLTALAKAAEENPELAAALGSDYTITPDIIVTRNLIAD
AEINRNEFLVDENIATYASLRAGNGNMPLLHASISCKWTIRSDRAQNARS
EGLNLVRNRKGRLPHIVVVTAEPTPSRISSIALGTGEIDCVYHFALYELE
QILQSLNYEDALDLFYIMVNGKRLKDISDLPLDLAV
Ligand information
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1fiu Structure of the tetrameric restriction endonuclease NgoMIV in complex with cleaved DNA.
Resolution1.6 Å
Binding residue
(original residue number in PDB)		D34 S36 R59 G62 G66 D140 K187 W188 T189 R191 R194
Binding residue
(residue number reindexed from 1)		D34 S36 R59 G62 G66 D140 K187 W188 T189 R191 R194
Enzymatic activity
Enzyme Commision number 3.1.21.4: type II site-specific deoxyribonuclease.
Gene Ontology
Molecular Function
GO:0004519 endonuclease activity
GO:0009036 type II site-specific deoxyribonuclease activity
GO:0046872 metal ion binding
Biological Process
GO:0009307 DNA restriction-modification system

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Molecular Function
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Biological Process
External links
PDB RCSB:1fiu, PDBe:1fiu, PDBj:1fiu
PDBsum1fiu
PubMed10966652
UniProtP31032|T2M4_NEIGO Type II restriction enzyme NgoMIV (Gene Name=ngoMIVR)

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