Structure of PDB 1dp4 Chain C Binding Site BS01

Receptor Information
>1dp4 Chain C (length=429) Species: 10116 (Rattus norvegicus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
SDLTVAVVLPLTNTSYPWSWARVGPAVELALARVKARPDLLPGWTVRMVL
GSSENAAGVCSDTAAPLAAVDLKWEHSPAVFLGPGCVYSAAPVGRFTAHW
RVPLLTAGAPALGIGVKDEYALTTRTGPSHVKLGDFVTALHRRLGWEHQA
LVLYADRLGDDRPCFFIVEGLYMRVRERLNITVNHQEFVEGDPDHYPKLL
RAVRRKGRVIYICSSPDAFRNLMLLALNAGLTGEDYVFFHLDVFGQSLKP
QKPWERGDGQDRSARQAFQAAKIITYKEPDNPEYLEFLKQLKLLADKKFN
FTVEDGLKNIIPASFHDGLLLYVQAVTETLAQGGTVTDGENITQRMWNRS
FQGVTGYLKIDRNGDRDTDFSLWDMDPETGAFRVVLNYNGTSQELMAVSE
HKLYWPLGYPPPDVPKCGFDNEDPACNQD
Ligand information
Ligand IDCL
InChIInChI=1S/ClH/h1H/p-1
InChIKeyVEXZGXHMUGYJMC-UHFFFAOYSA-M
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0		[Cl-]
FormulaCl
NameCHLORIDE ION
ChEMBL
DrugBankDB14547
ZINC
PDB chain1dp4 Chain C Residue 611 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1dp4 Structure of the dimerized hormone-binding domain of a guanylyl-cyclase-coupled receptor.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		P10 W18 S53 C86
Binding residue
(residue number reindexed from 1)		P10 W18 S53 C86
Annotation score1
Enzymatic activity
Enzyme Commision number 4.6.1.2: guanylate cyclase.
Gene Ontology

View graph for
Cellular Component
External links
PDB RCSB:1dp4, PDBe:1dp4, PDBj:1dp4
PDBsum1dp4
PubMed10894551
UniProtP18910|ANPRA_RAT Atrial natriuretic peptide receptor 1 (Gene Name=Npr1)

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