Structure of PDB 1btg Chain C Binding Site BS01

Receptor Information
>1btg Chain C (length=109) Species: 10090 (Mus musculus) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GEFSVCDSVSVWVGDKTTATDIKGKEVTVLAEVNINNSVFRQYFFETKCR
ASNPVESGCRGIDSKHWNSYCTTTHTFVKALTTDEKQAAWRFIRIDTACV
CVLSRKATR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1btg Chain C Residue 900 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1btg Nerve growth factor in different crystal forms displays structural flexibility and reveals zinc binding sites.
Resolution2.5 Å
Binding residue
(original residue number in PDB)		H84 D105
Binding residue
(residue number reindexed from 1)		H75 D96
Annotation score4
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0005102 signaling receptor binding

View graph for
Molecular Function
External links
PDB RCSB:1btg, PDBe:1btg, PDBj:1btg
PDBsum1btg
PubMed8201620
UniProtP01139|NGF_MOUSE Beta-nerve growth factor (Gene Name=Ngf)

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