Structure of PDB 1brk Chain C Binding Site BS01

Receptor Information
>1brk Chain C (length=107) Species: 1390 (Bacillus amyloliquefaciens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
INTFDGVADYLQTYHKLPDNYITKSEAQALGWVASKGNLADVAPGKSIGG
DIFSNREGKLPGKSGRTWREADINYTSGFRNSDRILYSSDWLAYKTTDHY
QTFTKIR
Ligand information
Ligand IDZN
InChIInChI=1S/Zn/q+2
InChIKeyPTFCDOFLOPIGGS-UHFFFAOYSA-N
SMILES
SoftwareSMILES
CACTVS 3.341[Zn++]
ACDLabs 10.04
OpenEye OEToolkits 1.5.0		[Zn+2]
FormulaZn
NameZINC ION
ChEMBLCHEMBL1236970
DrugBankDB14532
ZINC
PDB chain1brk Chain C Residue 111 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
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PDB1brk Structural and energetic responses to cavity-creating mutations in hydrophobic cores: observation of a buried water molecule and the hydrophilic nature of such hydrophobic cavities.
Resolution2.0 Å
Binding residue
(original residue number in PDB)		E60 K62
Binding residue
(residue number reindexed from 1)		E57 K59
Annotation score4
Enzymatic activity
Enzyme Commision number 3.1.27.-
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0004521 RNA endonuclease activity
GO:0004540 RNA nuclease activity

View graph for
Molecular Function
External links
PDB RCSB:1brk, PDBe:1brk, PDBj:1brk
PDBsum1brk
PubMed8605178
UniProtP00648|RNBR_BACAM Ribonuclease

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