Structure of PDB 1af6 Chain C Binding Site BS01
Receptor Information
>1af6 Chain C (length=421) Species:
562
(Escherichia coli) [
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VDFHGYARSGIGWTGSGGEQQCFQTTGAQSKYRLGNECETYAELKLGQEV
WKEGDKSFYFDTNVAYSVAQQNDWEATDPAFREANVQGKNLIEWLPGSTI
WAGKRFYQRHDVHMIDFYYWDISGPGAGLENIDVGFGKLSLAATRSSEAG
GSSSFASNNIYDYTNETANDVFDVRLAQMEINPGGTLELGVDYGRANLRD
NYRLVDGASKDGWLFTAEHTQSVLKGFNKFVVQYATDSMTSQGKGLSQGS
GVAFDNEKFAYNINNNGHMLRILDHGAISMGDNWDMMYVGMYQDINWDND
NGTKWWTVGIRPMYKWTPIMSTVMEIGYDNVESQRTGDKNNQYKITLAQQ
WQAGDSIWSRPAIRVFATYAKWDEKWGYDYTGNADNNANFGKAVPADFNG
GSFGRGDSDEWTFGAQMEIWW
Ligand information
Ligand ID
GLC
InChI
InChI=1S/C6H12O6/c7-1-2-3(8)4(9)5(10)6(11)12-2/h2-11H,1H2/t2-,3-,4+,5-,6+/m1/s1
InChIKey
WQZGKKKJIJFFOK-DVKNGEFBSA-N
SMILES
Software
SMILES
OpenEye OEToolkits 1.5.0
C(C1C(C(C(C(O1)O)O)O)O)O
OpenEye OEToolkits 1.5.0
C([C@@H]1[C@H]([C@@H]([C@H]([C@H](O1)O)O)O)O)O
CACTVS 3.341
OC[CH]1O[CH](O)[CH](O)[CH](O)[CH]1O
CACTVS 3.341
OC[C@H]1O[C@H](O)[C@H](O)[C@@H](O)[C@@H]1O
ACDLabs 10.04
OC1C(O)C(OC(O)C1O)CO
Formula
C6 H12 O6
Name
alpha-D-glucopyranose;
alpha-D-glucose;
D-glucose;
glucose
ChEMBL
CHEMBL423707
DrugBank
ZINC
ZINC000003861213
PDB chain
1af6 Chain F Residue 1 [
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Receptor-Ligand Complex Structure
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PDB
1af6
Channel specificity: structural basis for sugar discrimination and differential flux rates in maltoporin.
Resolution
2.4 Å
Binding residue
(original residue number in PDB)
R8 Y41 E43 R82 R109 D116 Y118
Binding residue
(residue number reindexed from 1)
R8 Y41 E43 R82 R109 D116 Y118
Annotation score
3
Enzymatic activity
Enzyme Commision number
?
Gene Ontology
Molecular Function
GO:0001618
virus receptor activity
GO:0005363
maltose transmembrane transporter activity
GO:0005515
protein binding
GO:0015144
carbohydrate transmembrane transporter activity
GO:0015288
porin activity
GO:0042958
maltodextrin transmembrane transporter activity
Biological Process
GO:0006811
monoatomic ion transport
GO:0006974
DNA damage response
GO:0015768
maltose transport
GO:0015774
polysaccharide transport
GO:0034219
carbohydrate transmembrane transport
GO:0042956
maltodextrin transmembrane transport
GO:0046718
symbiont entry into host cell
GO:1904981
maltose transmembrane transport
Cellular Component
GO:0009279
cell outer membrane
GO:0016020
membrane
GO:0046930
pore complex
GO:0106234
outer membrane protein complex
View graph for
Molecular Function
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Biological Process
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Cellular Component
External links
PDB
RCSB:1af6
,
PDBe:1af6
,
PDBj:1af6
PDBsum
1af6
PubMed
9299337
UniProt
P02943
|LAMB_ECOLI Maltoporin (Gene Name=lamB)
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