Structure of PDB 1a4e Chain C Binding Site BS01

Receptor Information
>1a4e Chain C (length=488) Species: 4932 (Saccharomyces cerevisiae) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DVREDRVVTNSTGNPINEPFVTQRIGEHGPLLLQDYNLIDSLAHFNRENI
PQRNPHAHGSGAFGYFEVTDDITDICGSAMFSKIGKRTKCLTRFSTVGGD
KGSADTVRDPRGFATKFYTEEGNLDWVYNNTPVFFIRDPSKFPHFIHTQK
RNPQTNLRDADMFWDFLTTPENQVAIHQVMILFSDRGTPANYRSMHGYSG
HTYKWSNKNGDWHYVQVHIKTDQGIKNLTIEEATKIAGSNPDYCQQDLFE
AIQNGNYPSWTVYIQTMTERDAKKLPFSVFDLTKVWPQGQFPLRRVGKIV
LNENPLNFFAQVEQAAFAPSTTVPYQEASADPVLQARLFSYADAHRYRLG
PNFHQIPVNCPYASKFFNPAIRDGPMNVNGNFGSEPTYLANDKSYTYIQQ
DRPIQQHQEVWNGPAIPYHWATSPGDVDFVQARNLYRVLGKQPGQQKNLA
YNIGIHVEGACPQIQQRVYDMFARVDKGLSEAIKKVAE
Ligand information
Ligand IDAZI
InChIInChI=1S/N3/c1-3-2/q-1
InChIKeyIVRMZWNICZWHMI-UHFFFAOYSA-N
SMILES
SoftwareSMILES
ACDLabs 10.04
CACTVS 3.341
OpenEye OEToolkits 1.5.0
[N-]=[N+]=[N-]
FormulaN3
NameAZIDE ION
ChEMBLCHEMBL79455
DrugBank
ZINC
PDB chain1a4e Chain C Residue 504 [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB1a4e Structure of catalase-A from Saccharomyces cerevisiae.
Resolution2.4 Å
Binding residue
(original residue number in PDB)
H70 F148
Binding residue
(residue number reindexed from 1)
H56 F134
Annotation score1
Enzymatic activity
Catalytic site (original residue number in PDB) H70 N143 A332
Catalytic site (residue number reindexed from 1) H56 N129 A318
Enzyme Commision number 1.11.1.6: catalase.
Gene Ontology
Molecular Function
GO:0004096 catalase activity
GO:0004601 peroxidase activity
GO:0005515 protein binding
GO:0020037 heme binding
GO:0046872 metal ion binding
Biological Process
GO:0000302 response to reactive oxygen species
GO:0006979 response to oxidative stress
GO:0042542 response to hydrogen peroxide
GO:0042744 hydrogen peroxide catabolic process
GO:0098869 cellular oxidant detoxification
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0005759 mitochondrial matrix
GO:0005777 peroxisome
GO:0005782 peroxisomal matrix

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Molecular Function

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Biological Process

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Cellular Component
External links
PDB RCSB:1a4e, PDBe:1a4e, PDBj:1a4e
PDBsum1a4e
PubMed9931255
UniProtP15202|CATA_YEAST Peroxisomal catalase A (Gene Name=CTA1)

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