Structure of PDB 8oit Chain Bv Binding Site BS01

Receptor Information
>8oit Chain Bv (length=238) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
GSPWRLLGALCLQRPPVVSKPLTPLQEEMASLLQQIEIERSLYSDHELRA
LDENQRLAKKKADLHDEEDEQDILLAQDLEDMWEQKFLQFKLGARITEAD
EKNDRTSLNRKLDRNLVLLVREKFGDQDVWILPQAEWQPGETLRGTAERT
LATLSENNMEAKFLGNAPCGHYTFKFPQAMRTESNLGAKVFFFKALLLTG
DFSQAGNKGHHVWVTKDELGDYLKPKYLAQVRRFVSDL
Ligand information
>8oit Chain B9 (length=72) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagaguguagcuuaacacaaagcacccaacuuacacuuaggagauuucaa
cuuaacuugaccgcucugacca
<<<<<<...<<<........>>>.<<.<<.......>>.>>.....<<<<
......>>>>..>>>>>>....
Receptor-Ligand Complex Structure
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PDB8oit Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution2.9 Å
Binding residue
(original residue number in PDB)		F165 Q168 V170 Q175 F215 K216 R222 K265
Binding residue
(residue number reindexed from 1)		F124 Q127 V129 Q134 F174 K175 R181 K224
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003674 molecular_function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0008150 biological_process
GO:0032543 mitochondrial translation
Cellular Component
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0030054 cell junction
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oit, PDBe:8oit, PDBj:8oit
PDBsum8oit
PubMed37141370
UniProtQ9H2W6|RM46_HUMAN Large ribosomal subunit protein mL46 (Gene Name=MRPL46)

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