Structure of PDB 8oit Chain Bp Binding Site BS01

Receptor Information
>8oit Chain Bp (length=147) Species: 9606 (Homo sapiens) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
DPKKDQEAKERLKRKIRKLEKATQELIPIEDFITPLKFLDKARERPQVEL
TFEETERRALLLKKWSLYKQQERKMERDTIRAMLEAQQEALEELQLESPK
LHAEAIKRDPNLFPFEKEGPHYTPPIPNYQPPEGRYNDITKVYTQVE
Ligand information
>8oit Chain B9 (length=72) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
cagaguguagcuuaacacaaagcacccaacuuacacuuaggagauuucaa
cuuaacuugaccgcucugacca
<<<<<<...<<<........>>>.<<.<<.......>>.>>.....<<<<
......>>>>..>>>>>>....
Receptor-Ligand Complex Structure
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PDB8oit Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution2.9 Å
Binding residue
(original residue number in PDB)
F88 S122 L123 K125 Q126
Binding residue
(residue number reindexed from 1)
F32 S66 L67 K69 Q70
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0005515 protein binding
Biological Process
GO:0009653 anatomical structure morphogenesis
GO:0032543 mitochondrial translation
Cellular Component
GO:0005634 nucleus
GO:0005730 nucleolus
GO:0005739 mitochondrion
GO:0005743 mitochondrial inner membrane
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:1990904 ribonucleoprotein complex

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Cellular Component
External links
PDB RCSB:8oit, PDBe:8oit, PDBj:8oit
PDBsum8oit
PubMed37141370
UniProtQ9NQ50|RM40_HUMAN Large ribosomal subunit protein mL40 (Gene Name=MRPL40)

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