Structure of PDB 8oin Chain Bn Binding Site BS01

Receptor Information
>8oin Chain Bn (length=354) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RRAAPLGPMPNEDIDVSDLERLKKYRSFDRYRRRAEQEARKPHWWRTYRE
HFGEESGPKDRVDIGLPPPKVSRTQQLLERKQALRELRANVEEERAARLQ
TARIPLEAVRAEWERTCGPYHKQRLAEYCGLYRDLFHGATFVPRVPLHVA
YAVGEDDLMPVYHGNEVTPTEAAQAPEVTYEADEGSLWTLLLTNLDGHLL
EPDAEYVHWLVTNIPGNRVTEGQETCPYLPPFPARGSGFHRFAFLLFKQD
KRIDFSGDTRPSPCYQLAQRTFHTFDFYKKHQDAMTPAGLAFFQCRWDDS
VTRVFHQLLDMREPVFEFVRPPPYHPKQKRFPHRQPLRYLDRYRDSHEPT
YGIY
Ligand information
>8oin Chain B8 (length=1571) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacuc
aaccacaaagggauaaaacauaacuuaacauggacuagcaauuucgguug
gggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagacaa
accagucaaaauaaccauaacaucacuuauugauccaaaauuuugaucaa
cggaacaaguuacccuagggauaacagcgcaauccuguucuagaguuccu
aucgacaauaggguuuacgaccucgauguuggaucaggacacccaaaugg
ugcaaccgcuauuaaagguucguuuguucaacgauuaaaguccuacguga
ucugaguucagaccggagcaauccaggucgguuucuaucuauuauaaauu
ucucccaguacgaaaggacaagagaaaugggaccaaccucacaaacgcgu
cucagagauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaau
ccagcccuagaacagggcaca
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..>.>>..<<<<<.....<<<<....>>>>..<<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>.>....<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
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>......<<<..<<<<<<<.................>>>>>>>.......
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<.........<.....<<<<<<<<..<<<.........>>>...<<<<<<
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<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<........
....................>>>>>>....>>>>.>>>.>>>>..<<<<.
....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<..
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.......>>>>..>>>>>>.......<<<..<.<<<<<<...<<......
.>>...>>>>>>...>.>>.>.......<.<<<.<<<<<<..<<.<<<<<
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>>>..>....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<
<<<<.................>>>>>>><<<<<...<.........>.>>
>>>.<<<...<<<<.<............>..>>>>...>>>.>>......
...<<<<.......>>>>...
Receptor-Ligand Complex Structure
Global viewLocal viewStructure summary

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PDB8oin Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution3.6 Å
Binding residue
(original residue number in PDB)
R27 H351 P352 R356 H359 R360 R364 R368 G378 I379 Y380
Binding residue
(residue number reindexed from 1)
R1 H325 P326 R330 H333 R334 R338 R342 G352 I353 Y354
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Cellular Component
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005829 cytosol
GO:0005840 ribosome

View graph for
Cellular Component
External links
PDB RCSB:8oin, PDBe:8oin, PDBj:8oin
PDBsum8oin
PubMed37141370
UniProtF1RW03

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