Structure of PDB 6z1p Chain Bh Binding Site BS01

Receptor Information

>6z1p Chain Bh (length=256) Species: 312017 (Tetrahymena thermophila SB210)

MKQLKKIMINKTKIMSNDIIYIKRTYHQKIVNLKIYNNFKTEPKFYNLKF
IEFQNLLNNVNLNKVFYTEYTSYPLEDRFATSKFHTFDSYLTSLELIDCT
FLKKKFNYKYKYSMFTYFIPFLIKNGKKLSTINFILKGISTIYDNLKYNK
LSQFESYSYVNQFKHYIDTADDVYNINFLIHWIINIYKPVFDVIVYLSEK
NRLKTAYKHISTCIRQDNSAKLNNRITNIFLDLLLNYKKSYLYTRKMYIY
EQVMDM

Ligand information

>6z1p Chain Bb (length=1385)

uguuuacagcuuaaagauuauuuuguacaauauuagguaauuauuucuaa
aacuguuuaauaauauuauuuuuaguaaaauaagccuagauguuuaguug
aauuuagagauuguucaaccacauacggguaugaaaacuacccuaucuuu
uugacagcagugaggaauuuuggacaauaugcgaaagcaugauccagcga
acuaauggaaacgaagaagauagcaauauuguaaaguuuagugcgagaau
uaacaaaugaguaaauucuaggagaagcucuggcuaauacaugugccagc
agccgcgguaauacaugaggagcaagcguuacccacauugacugggugua
uuaaauacauaggugauuacaaauacuacuuuaaaagucaauuaaaaacc
uaauauaguaguuuuuuuguaaaugauaauuaaauauaaggauaggagau
uuauagaacaacgauuaaauguaguuacacuauagagcuugccauaaacu
aaggugcuuuccuauauuuaauuauagcugauguaugaaaguacggggau
cgauaaggauuaguuucccuaguaguccguacuguaaaagaugaauacuu
caugaauuaaauauucagggauagcuaacgcaaaguauucuacucgggga
guauaaucgcaagauuaaaacuuaacugaauuggcgggaauuuguucgaa
cgguggaacaugugguuuaaugcgauaauccacgcaaaaucuuaccaacg
uuucaggcuuuaucaguaguaugauuaauaucaaaauuauaugauuuagu
acggaauugcauggcugucgucaguucgugcugugaaguuuaggauuaag
uucuuuuuaacgaaugcaacccuauaaguaaguuuuuauuuuaaaauaac
uuaauuuuuuaaauauacuuauuuaaucuauaauuagaauauauugaauc
uauucuguauauucuuuuauagggguuauaggcugaagucaagucccuau
ggucuuuauacguugggcuacacacguguuacaaggguaaauacaaaaag
acgcaaaaaaguaauuuugagcaaaccuuuaaaaauuaccuuaguucaga
uuguuuuaugaaauucuaaaacaugaagaugaaaucguuaguaauuguaa
auuauuauguuacagugaaacaauagucaaauuuugcacacaccgcccau
cacgcucggaaagucaauaauagcggaagauuugaaaaacucugcgcaaa
acuaauauuauuuuuauauuaguuggcauuauauuauuuuuuaauggcau
gguugaaaaguaguauccaaucuaguauugguaauuugagugaaguugac
acaagguacugguaggggaaccuguugguggaaua

............................<<<....<<<..<<<<<<<<<<
<.......<<<<....>>>>>>>>>..>>>>>>>>>.....>>>..<<<<
<<<<....>>>>...>>>>....<<.<<<<.........>>>>>><<...
..>>.................<<<...<<<<<....>>>>.>>>>.....
........<<<<......<<<<....>>>>.....>>>>......<<<<<
..<........>..>>>>>.......<<<<<(((.....<<<<.....<<
.)))>>.......>>>>.>>>>>.....................<<<((.
....<<<<<..<<<.<<<<<<<<..<<<<<.<<.................
...>>.>>>>>....>>>>>>.>>..<<<<<<<<<<<.<<<<.<<<<<.<
<<<<<<....<<<......>>>.......>>>>>>.>>>>.......<<.
...>>.>>.>>>>>>>>>>>>>>>..>>>..>>>>>...<<<<<<<<...
<....<<<.........>>>....>>>>>>>>>.........<<<<<<.<
<.<<<<.......>>>>..>>..<<..))>>...>>>>>>.>>>.<<<..
...<<<<<....>>>>>...>>>.........<<<<.<<<<<<<.....<
<<<<..<<<<<<<<<<......<<........>>..........<<<<<<
<.....<<<..<<<..<<<..<<<<....>>>>...>>>...>>>..>>>
..<<.<<<..<<<<<<.......<<<<<<<<<....>>>...<<<.....
.>>>.....>>>>>>.....<<<.<<<<<<<<....<<<<<.<<<<....
.....>>>>.>>>>>..>>>>>>>>..<<<<<<...<<<<<<<<.<<...
...>>.>>>>>>>>..>>>>>>.......>>>.........>>>...>>>
>>>>>....>>>>>>>...>>.>>>>>>>>.....<<<<<.<....<<<<
..<<..<<<<....>>>>..>>....>>>>....>>>>>>......<...
.<<<<<<<........>>>>>>>....>.....>>>>>.....<<<<<<<
.........>>>>>>>...........>>>>>>>>>>.>........<<.
<.<<<<<<<<..<<<<<<<.<<<.....<<<.<......<.<<<.<<..<
<<<<<<<<.......>>>>>>>>>.......<...........>..>>.>
>>..>.......>.>>>....>>>.>>>>>>>..>>>>>>>>..>.>>..
.......<<<<<<<<<....>>>>>>>>>......

Receptor-Ligand Complex Structure

Structure summary

• PDB: 6z1p Ciliate mitoribosome illuminates evolutionary steps of mitochondrial translation.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): K105 F106 K111 P120 F121 L122 N125 G126 S130 V215 K228 R235 A240 L242
• Binding residue (residue number reindexed from 1): K105 F106 K111 P120 F121 L122 N125 G126 S130 V195 K208 R215 A220 L222

Gene Ontology

Cellular Component

• GO:0005739 mitochondrion

External links

• PDB: RCSB:6z1p, PDBe:6z1p, PDBj:6z1p
• PDBsum: 6z1p
• PubMed: 32553108
• UniProt: Q951A4