Structure of PDB 6gaw Chain Bh Binding Site BS01

Receptor Information
>6gaw Chain Bh (length=289) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
AKKGFRAAYRFQKELERWRLLRCPPPPVRRSEKPNWDYHAEIQAFGHRLQ
ETFSLDLLKTAFVNSCYIKSEEAKRQKLGIDKEAALLNLKDNQELSEQGI
SFSQTCLTQFFEDAFPDLPTEGVTSLVDFLTSEEVVCHVARNLAVEQLAL
SAEFPVPPPVLRQTFFAVIGALLQSSGPERTALFIRDFLITQMTGKELFE
MWTITNPMGLLVEELKKRKISAPESRLTRQSGSTTALPVYFVGLYCDRKL
IAEGPGETVLVAEEEAARVALRKLFGFTENRRPWDYSKP
Ligand information
>6gaw Chain BA (length=1549) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacua
acuuaacauggacuagcaauuucgguuggggugaccucggaguacaaaaa
acccuccgagugauuuuaaucuagacaaaccagucaaaauaaccauaaca
ucacuuauugauccaaaauuuugaucaacggaacaaguuacccuagggau
aacagcgcaauccuguucuagaguuccuaucgacaauaggguuuacgacc
ucgauguuggaucaggacacccaaauggugcaaccgcuauuaaagguucg
uuuguucaacgauuaaaguccuacgugaucugaguucagaccggagcaau
ccaggucgguuucuaucuauuauaaauuucucccaguacgaaaggacaag
agaaaugggaccaaccucacaaacgcgucucagagauaauuaaugauuua
aucuuaaccuaauuaacucauaauaaauccagcccuagaacagggcaca
<<.<......<<<<....................................
...<......>.................<<.....>>.............
.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<...<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>....
..>.>>..<<<<<.....<<<<....>>>>...<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>......<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
.<....<<<.........>>>....>.......<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<<..>>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<...............<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>....<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>....>>.>>>>>>......>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<......>>
>>>>....>>>>.>>>.>>>>..<<<<.....>>>><<<<<<........
...>>>>>>.<<<<....<<...<<<......>>>...>>.........>
>>>..........<<<....>>>............>>>>..>>>>>>...
....<<<..<.<<<<<<...<<.......>>...>>>>>>...>.>>.>.
......<<<<<..<<<<<..<<.<<<<<<......>>>>>>...>>.<<<
<<.....>>>>>.....>>>>>......>>>.>>....<<<<<<<....>
>>.>>>>....>>..>>>>>>.<<.<<<<<<<.................>
>>>>>><<<<<...............>>>>>.<<<...<<<<.<......
......>..>>>>...>>>.>>.........<<<<.......>>>>...
Receptor-Ligand Complex Structure
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PDB6gaw Unique features of mammalian mitochondrial translation initiation revealed by cryo-EM.
Resolution3.2 Å
Binding residue
(original residue number in PDB)		A31 K33 F35 R36 Y39 F41 W48 R52
Binding residue
(residue number reindexed from 1)		A1 K3 F5 R6 Y9 F11 W18 R22
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003723 RNA binding
GO:0003725 double-stranded RNA binding
GO:0004525 ribonuclease III activity
Biological Process
GO:0006396 RNA processing
GO:0070125 mitochondrial translational elongation
Cellular Component
GO:0005634 nucleus
GO:0005654 nucleoplasm
GO:0005739 mitochondrion
GO:0005762 mitochondrial large ribosomal subunit
GO:0005840 ribosome
GO:0005886 plasma membrane
GO:0016604 nuclear body
GO:0070877 microprocessor complex
GO:1990904 ribonucleoprotein complex

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Molecular Function
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Biological Process
View graph for
Cellular Component
External links
PDB RCSB:6gaw, PDBe:6gaw, PDBj:6gaw
PDBsum6gaw
PubMed30089917
UniProtF1SR64

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