Structure of PDB 4v92 Chain Bf Binding Site BS01

Receptor Information

>4v92 Chain Bf (length=64) Species: 28985 (Kluyveromyces lactis)

AAKKAAAAAKAAAVLSYYKVDAEGKVTKLAAACSNPTCGAGVFLANHKDR
LYCGKCHSVYKVNA

Ligand information

>4v92 Chain A2 (length=1764)

uaucugguugauccugccaguagucauaugcuugucucaaagauuaagcc
augcaugucuaaguauaagcaauuuauacagugaaacugcgaauggcuca
uuaaaucaguuaucguuuauuugauaguuccuuuacuacaugguauaacu
gugguaauucuagagcuaauacaugcuuaaaaucucgacccuuuggaaga
gauguauuuauuagauaaaaaaucaaugucuucggacucuuugaugauuc
auaauaacuuuucgaaucgcauggccuugugcuggcgaugguucauucaa
auuucugcccuaucaacuuucgaugguaggauaguggccuaccaugguuu
caacggguaacggggaauaaggguucgauuccggagagggagccugagaa
acggcuaccacauccaaggaaggcagcaggcgcgcaaauuacccaauccu
aauucagggagguagugacaauaaauaacgauacagggcccauucggguc
uuguaauuggaaugaguacaauguaaauaccuuaacgaggaacaauugga
gggcaagucuggugccagcagccgcgguaauuccagcuccaauagcguau
auuaaaguuguugcaguuaaaaagcucguaguugaacuuugggcccgguu
ggccggucggauuuccaacggggccuuuccuucuggcuaaccuugagucc
uuguggcucuuggcgaaccaggacuuuuacuuugaaaaaauuagaguguu
caaagcaggcguauugcucgaauauauuagcauggaauaauagaauagac
guuugguucuauuuuguugguuucuaggaccaucguaaugauuaauaggg
acggucgggggcaucaguauucaauugucagaggugaaauucuuggauuu
auugaagacuaacuacugcgaaagcauuugccaaggacguuuucauuaau
caagaacgaaaguuaggggaucgaagaugaucagauaccgucguagucuu
aaccauaaacuaugccgacuagggaucgggugguguuuuuuuaaugaccc
acucggcaccuuacgagaaaucaaagucuuuggguucuggggggaguaug
gucgcaaggcugaaacuuaaaggaauugacggaagggcaccaccaggagu
ggagccugcggcuuaauuugacucaacacggggaaacucaccagguccag
acacaauaaggauugacagauugagagcucuuucuugauuuugugggugg
uggugcauggccguucuuaguugguggagugauuugucugcuuaauugcg
auaacgaacgagaccuuaaccuacuaaauaguggugcuagcauuugcugg
uuauccacuucuuagagggacuaucgguuucaagccgauggaauuugagg
caauaacaggucugugaugcccuuagacguucugggccgcacgcgcgcua
cacugacggagccagcgagucuaaccuuggccgagaggucuugguaaucu
uggaaacuccgucgugcuggggauagagcauuguaauuauugcucuucaa
cgaggaauuccuaguaagcgcaagucaucagcuugcguugauuacguccc
ugcccuuuguacacaccgcccgucgcuaguaccgauugaauggcuuagug
aggccucaggaucugcuuagagaucucagagcggagaauuuggacaaacu
uggucauuuagaggaacuaaaagucguaacaagguuuccguaggugaacc
ugcggaaggaucau

...<<<<<.{.((((>>>>><<<<.<<<<<<...<.<..........<<.
.<<<..<<....<<....<<..........>>...>>.>>......<<..
......<<<..<<..<<....<<<..................<.....<<
.<<<.....>>>.>>......>.........<<<<<..<<....>>..>>
>>>....<<<<<<......((((.{..<<.<..>.>>.............
.>>>>>>.........<<<<..<<<.....>>>.>>>>....>>>...>>
>>..>>>.<<<....<<<....<<<<<<<<.......>>>>>>>>>>>..
....>>>...<<<.<<<......>>>....>>>.>>.<<.<<<.......
...>>>.>>.<.<<....>>.>...>>>.>>.........<<<....<<<
.....>>>..>>>.......>.>.....<..<<<<<<..<<....>>..>
>>>>>....>.....<<..<...........>..>>.........<<<<<
((......<<<<.....<<..))>>.......>>>>.>>>>>..>>>>>>
>>>>.........<<<[[.....<.<<...<<<.<<....<<<<<<.<<<
<<....<..>....>>>>>.>>>>>>.....<<<<<....<......<..
.....>......>....>>>>>....<<<<<.<<.......<<...<...
....>..<<<.....>>>....>>......>>.>>..>>>........<<
...<<<<<<<.......}.))))..>>>>>>>..>>.....>>....<<<
<<<.<<...<<<<..<<<.<<<<<<.<...<<<......>>>......>.
>>>>>>.>>>.......<<....>>...>>>>...>>>>>.>>>...>>>
...>>.>....<<<<<<<...<...<<<<.<.....>.>>>>...>>>>>
>>>..........<<<.<<.<<<..<<<<<<<<..<<........>>.>>
>>>>>>..>>>...<<..]]>>...>>.....>>>.>>>.<<<......<
<<......>>>....>>>..)))).}...<<.<<<<<<<..<<.<<<<<.
...<<.<<<<<<......<<........>>..........<<<<<.....
.<<<<<........<<.<<<........>>>.>>......>>>>>...<<
.<<<..<<.<<.<<<....<<<.<<.<......>....<<<......>>>
...>>.>>>....<<<<..<<..<<<<..<<<<<.<..<<<....>>>..
>...>>>>>..>>>>.>>....<<<<<<.....>>>>>>.......>>>>
....>>>..>>.....>>>>>>>.......>>>>>...>>.>>>>.>>..
....<<<<<<<......<<.....<<..<<<<....>>>>..>>....>>
......>>>>>>>...........<<<<<<..........>>>>>>....
.......>>>>>....<<<<<<<<.......>>>>>>>>......>>...
>>>>>>>>>...........<<.<..<<<<.<<....<<<<<<<<.<<<.
.<.<<..<....<<.<<<.<<....>>.>>>.>>....>..>>.>..>>>
.>>>>>>>>...>>.>>>>...>.>>..........<<<<<<<<....>>
>>>>>>........

Receptor-Ligand Complex Structure

Structure summary

• PDB: 4v92 Initiation of Translation by Cricket Paralysis Virus Ires Requires its Translocation in the Ribosome.
• Resolution: 3.7 Å
• Binding residue (original residue number in PDB): A89 A90 K91 K92 A93 A94 A95 A96 A97 K98 A99 A100 A133 N134 H135 K136 D137 R138 L139 Y140 C141 G142 H145 S146 V147 Y148
• Binding residue (residue number reindexed from 1): A1 A2 K3 K4 A5 A6 A7 A8 A9 K10 A11 A12 A45 N46 H47 K48 D49 R50 L51 Y52 C53 G54 H57 S58 V59 Y60

Gene Ontology

--> -->

UnboundLocalError

Python 3.6.8: /usr/bin/python3 Tue Dec 3 01:58:02 2024

A problem occurred in a Python script. Here is the sequence of function calls leading up to the error, in the order they occurred.

 /var/www/html/BioLiP/pdb.cgi in <module>()

   1435     title=pdb2title(pdbid)

   1436     if bs.startswith("BS"):

=> 1437         pubmed,uniprot=display_interaction(pdbid,asym_id,bs,title)

   1438     else:

   1439         if lig3:

pubmed = '', uniprot = '', display_interaction = <function display_interaction>, pdbid = '4v92', asym_id = 'Bf', bs = 'BS01', title = 'Initiation of Translation by Cricket Paralysis V... Ires Requires its Translocation in the Ribosome.'

 /var/www/html/BioLiP/pdb.cgi in display_interaction(pdbid='4v92', asym_id='Bf', bs='BS01', title='Initiation of Translation by Cricket Paralysis V... Ires Requires its Translocation in the Ribosome.')

   1295         display_ec(ec,csaOrig,csaRenu)

   1296     if go:

=> 1297         display_go(go,uniprot,pdbid,asym_id)

   1298     return pubmed,uniprot

   1299 

global display_go = <function display_go>, go = '0003735,0005840,0006412', uniprot = '', pdbid = '4v92', asym_id = 'Bf'

 /var/www/html/BioLiP/pdb.cgi in display_go(go='0003735,0005840,0006412', uniprot='', pdbid='4v92', asym_id='Bf')

    480         '''.replace("$namespace_link",namespace_link

    481           ).replace("$namespace",namespace

=>  482           ).replace("$uniprot",u

    483         ))

    484         for l,(term,name) in enumerate(go2aspect[Aspect]):

u undefined

UnboundLocalError: local variable 'u' referenced before assignment
      args = ("local variable 'u' referenced before assignment",)
      with_traceback = <built-in method with_traceback of UnboundLocalError object>