Structure of PDB 8oiq Chain Be Binding Site BS01

Receptor Information
>8oiq Chain Be (length=94) Species: 9823 (Sus scrofa) [Search protein sequence] [Download receptor structure] [Download structure with residue number starting from 1] [View receptor structure]
RNRIPGRQWIGKHRRPRPVSAQAKQNMIRRLETEAENQYWLSRPFLTAEQ
ERGHAAVRRAAAFQALKAAQAARFPAHRRLEEQLGHLLVTRKWS
Ligand information
>8oiq Chain B8 (length=1571) [Search RNA sequence] [Download ligand structure] [Download structure with residue number starting from 1] [View ligand structure]
accaaagcuagcucaacauacuaaacaaauacaaaaauacaccaaaauaa
aauaaaacauucaccuaacauuaaaguauaggagauagaaauuuuuaucc
ugacgcuauagagauaguaccguaagggaaagaugaaagaauaaaauaaa
aguaaaaaaaagcaaagauuaccccuucuaccuuuugcauaaugguuuaa
ccagaaaaaaucuaacaaagagaacuuuagcuagauaccccgaaaccaga
cgagcuacccaugagcaguuuaaaagaaccaacucaucuauguggcaaaa
uagugagaagacuuguagguagaggugaaaagccuaacgagccuggugau
agcugguuguccgagaaagaauuuuaguucaaccuuaaaaauaccccaaa
aacccuaaauuccaauguauuuuuaagagauagucuaaaaagguacagcu
uuuuagaaacggauacaaccuugacuagagaguaaaaucuuaauacuacc
auaguaggccuaaaagcagccaucaauugagaaagcguuaaagcucaaca
aauucaccaacauaaucccaaaaacuaauaacaaacuccuagcccaauac
cggacuaaucuauugaaacauagaagcaauaauguuaauaugaguaacaa
gaagccuuucuccucgcacacgcuuacaucaguaacuaauaauauacuga
uaauuaacaaccaauaaaccaaaacaacacuaaaacguuuauuaauuaca
uuguuaacccaacacaggagugcaccaaggaaagauuaaaagaaguaaaa
ggaacucggcaaacacaaaccccgccuguuuaccaaaaacaucaccucua
gcauuacuaguauuagaggcaaugccugcccagugacaccaguuuaacgg
ccgcgguauucugaccgugcaaagguagcauaaucacuuguucuccaaau
aaggacuuguaugaauggccacacgaggguuuuacugucucuuacuucca
aucagugaaauuaaccuucccgugaagaggcgggaauaaaaaaauaagac
gagaagacccuauggagcuuuaauuaacuauuccaaaaguuaaacaacuc
aaccacaaagggauaaaacauaacuuaacauggacuagcaauuucgguug
gggugaccucggaguacaaaaaacccuccgagugauuuuaaucuagacaa
accagucaaaauaaccauaacaucacuuauugauccaaaauuuugaucaa
cggaacaaguuacccuagggauaacagcgcaauccuguucuagaguuccu
aucgacaauaggguuuacgaccucgauguuggaucaggacacccaaaugg
ugcaaccgcuauuaaagguucguuuguucaacgauuaaaguccuacguga
ucugaguucagaccggagcaauccaggucgguuucuaucuauuauaaauu
ucucccaguacgaaaggacaagagaaaugggaccaaccucacaaacgcgu
cucagagauaauuaaugauuuaaucuuaaccuaauuaacucauaauaaau
ccagcccuagaacagggcaca
<<.<......<<<<....................................
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.>>.>>.............<<....>>...................>...
.>>...........<<<.......>>>...<.<........>.>..<<<<
<........<<<<<.<..<<....>>...>.>>>>>..<<.<..<<<<<.
<.....<<<.<<<<<..<<<......>>>...<<<..<<<<........>
>>>.>>>....>>>>>.>>>...<<<.....>>>......>.>>>>...>
..>.>>..<<<<<.....<<<<....>>>>..<<<<<<<<<<<<.....<
<........>>.....>>>>>>>>>>>.>....<<<<<<<<<......>>
>>>>>>>...<<......>>....<<<<.<<<..................
......<<<.........>>>............<<<......>>>.....
...................................>>>>>>>........
>>>>>...<<<<<......>>>>>.........>>>>>.<......<<..
<<<....>>><<<<.<<<<........<<<<<....<<....>>..>>>>
>......<<<..<<<<<<<.................>>>>>>>.......
>>>.....<<......>>.>>>>....>>>>..<<<<....<<<<<<<.<
<.........<.....<<<<<<<<..<<<.........>>>...<<<<<<
.............>>>>>>...<<<<.<<<..<<<<<....>>>..>>>>
><<<<<<......>>>>>>........<...........<<<<<......
.>>>>>.....>....>>>.>..>>.>>>>>>...>..>>.>>>>>>>.>
>>>.>>.....>.....<<<<<........>>>>>.......<<<.<<<.
<<......<<<<.<<<<<<..<<<<..<<<.<<<<.<<<<<<........
....................>>>>>>....>>>>.>>>.>>>>..<<<<.
....>>>><<<<<<...........>>>>>>.<<<<....<<...<<<..
....>>>...>>.........>>>>..........<<<....>>>.....
.......>>>>..>>>>>>.......<<<..<.<<<<<<...<<......
.>>...>>>>>>...>.>>.>.......<<<<<.<<<<<<..<<.<<<<<
<......>>>>>>...>>.<<<<<.....>>>>>.....>>>>>..>...
>>>.>>....<<<<<<<....>>>.>>>>....>>..>>>>>>.<<.<<<
<<<<.................>>>>>>><<<<<...<.........>.>>
>>>.<<<...<<<<.<............>..>>>>...>>>.>>......
...<<<<.......>>>>...
Receptor-Ligand Complex Structure
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PDB8oiq Molecular basis of translation termination at noncanonical stop codons in human mitochondria.
Resolution3.5 Å
Binding residue
(original residue number in PDB)		R9 R11 I12 P13 G14 R15 Q16 W17 G19 K20 R22 R23 R25 P26 S28 Q33 N34 R37 R60 G61 A63 R66 R67 F71 K75 Q78 R81 R86 H94
Binding residue
(residue number reindexed from 1)		R1 R3 I4 P5 G6 R7 Q8 W9 G11 K12 R14 R15 R17 P18 S20 Q25 N26 R29 R52 G53 A55 R58 R59 F63 K67 Q70 R73 R78 H86
Enzymatic activity
Enzyme Commision number ?
Gene Ontology
Molecular Function
GO:0003735 structural constituent of ribosome
Biological Process
GO:0006412 translation
Cellular Component
GO:0005739 mitochondrion
GO:0005761 mitochondrial ribosome
GO:0005762 mitochondrial large ribosomal subunit

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Molecular Function
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Biological Process
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Cellular Component
External links
PDB RCSB:8oiq, PDBe:8oiq, PDBj:8oiq
PDBsum8oiq
PubMed37141370
UniProtA0A287BP93

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